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Point-of-care ultrasound (PoCUS) is a promising technique for diagnosing LBFs and assessing the success of reduction attempts. This article offers a comprehensive review of the use of PoCUS for the diagnosis and reduction of LBFs.<\/jats:p><\/jats:sec><jats:sec id=\"S1481803516003973_abs2\" sec-type=\"general\"><jats:title>Data source<\/jats:title><jats:p>MEDLINE and EMBASE databases were searched through July 19, 2015.<\/jats:p><\/jats:sec><jats:sec id=\"S1481803516003973_abs3\" sec-type=\"general\"><jats:title>Study selection<\/jats:title><jats:p>We included prospective studies that assessed test characteristics of PoCUS in 1) the diagnosis or 2) the reduction of LBFs. The methodological quality of the included studies was evaluated using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool.<\/jats:p><\/jats:sec><jats:sec id=\"S1481803516003973_abs4\" sec-type=\"general\"><jats:title>Data extraction<\/jats:title><jats:p>Thirty studies met inclusion criteria (n=3,506; overall fracture rate 48.0%). Test characteristics of PoCUS for the diagnosis of LBFs were as follows: sensitivity 64.7%\u2013100%, specificity 79.2%\u2013100%, positive likelihood ratio (LR) 3.11\u2013infinity, and negative LR zero\u20130.45. Sensitivity and specificity for the adequate reduction of LBFs with PoCUS were 94%\u2013100% and 56%\u2013100%, respectively. PoCUS diagnosis of pediatric forearm fractures in 10 studies showed a pooled sensitivity of 93.1% (95% confidence interval [CI], 87.2%\u201396.4%) and specificity of 92.9% (95% CI, 86.6%\u201396.4%), and PoCUS diagnosis of adult ankle fractures in four studies showed a pooled sensitivity of 89.5% (95% CI, 77.0%\u201395.6%) and specificity of 94.2% (95% CI, 86.1%\u201397.7%).<\/jats:p><\/jats:sec><jats:sec id=\"S1481803516003973_abs5\" sec-type=\"conclusion\"><jats:title>Conclusion<\/jats:title><jats:p>PoCUS demonstrates good diagnostic accuracy in all LBFs studied, especially in pooled results of diagnosis of pediatric forearm and adult ankle fractures. PoCUS is an appropriate adjunct to plain radiographs for LBFs.<\/jats:p><\/jats:sec>","DOI":"10.1017\/cem.2016.397","type":"journal-article","created":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T04:36:15Z","timestamp":1480912575000},"page":"131-142","source":"Crossref","is-referenced-by-count":57,"title":["Use of point-of-care ultrasound in long bone fractures: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"19","author":[{"given":"Lucas B.","family":"Chartier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Bosco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Lapointe-Shaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Chenkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,12,5]]},"reference":[{"key":"S1481803516003973_ref46","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2014.02.031"},{"key":"S1481803516003973_ref21","first-page":"409","article-title":"Ultrasound as a viable alternative to standard X-rays for the diagnosis of distal forearm fractures in children","volume":"150","author":"Eckert","year":"2012a","journal-title":"Z Orthop Unfall"},{"key":"S1481803516003973_ref19","unstructured":"R Core Team . 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