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We describe a case of a healthy 18-year-old female diagnosed with infectious mononucleosis who also presented with right upper quadrant abdominal pain, moderate transaminitis, and cholestatic biochemistry. An ultrasound revealed acute acalculous cholecystitis, generally a condition seen in the context of critical illness. Further investigating emergency department patients with infectious mononucleosis is often not indicated, but may be important for those who present atypically.<\/jats:p>","DOI":"10.1017\/cem.2018.15","type":"journal-article","created":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T07:15:29Z","timestamp":1519888529000},"page":"154-156","source":"Crossref","is-referenced-by-count":8,"title":["Infectious mononucleosis - not always a benign condition: a case report of infectious mononucleosis\u2013associated acute acalculous cholecystitis"],"prefix":"10.1007","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0248-8145","authenticated-orcid":false,"given":"Andrew","family":"Cameron","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kosalan","family":"Akilan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Carr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,3,1]]},"reference":[{"key":"S1481803518000155_ref2","first-page":"234","article-title":"Prospective study of the natural history of infectious mononucleosis caused by Epstein-Barr virus","volume":"14","author":"Rea","year":"2001","journal-title":"J Am Board Fam Pract"},{"key":"S1481803518000155_ref1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400046313"},{"key":"S1481803518000155_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.10.073"},{"key":"S1481803518000155_ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-197811000-00010"},{"key":"S1481803518000155_ref5","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-200006000-00016"},{"key":"S1481803518000155_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-003-0067-x"},{"key":"S1481803518000155_ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-007-6115-y"},{"key":"S1481803518000155_ref4","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1128\/JCM.32.1.259-261.1994","article-title":"Comparative evaluation of nine kits for rapid diagnosis of infectious mononucleosis and Epstein-Barr virus-specific serology","volume":"32","author":"Linderholm","year":"1994","journal-title":"J Clin Microbiol"},{"key":"S1481803518000155_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.hepres.2005.06.005"},{"key":"S1481803518000155_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2016.06.017"},{"key":"S1481803518000155_ref12","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.883245"},{"key":"S1481803518000155_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2007.10.005"},{"key":"S1481803518000155_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinmicnews.2011.12.003"},{"key":"S1481803518000155_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2015.04.004"},{"key":"S1481803518000155_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197901000-00016"}],"container-title":["CJEM"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1481803518000155","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T23:54:10Z","timestamp":1609458850000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1481803518000155\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,1]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["S1481803518000155"],"URL":"https:\/\/doi.org\/10.1017\/cem.2018.15","relation":{},"ISSN":["1481-8035","1481-8043"],"issn-type":[{"value":"1481-8035","type":"print"},{"value":"1481-8043","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,1]]}}}