{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T08:30:32Z","timestamp":1781598632392,"version":"3.54.5"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T00:00:00Z","timestamp":1536710400000},"content-version":"unspecified","delay-in-days":11,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CJEM"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec id=\"S1481803518004220_abs1\" sec-type=\"general\"><jats:title>Clinical question<\/jats:title><jats:p>Does the addition of topical tranexamic acid to anterior nasal packing decrease bleeding in patients with epistaxis who are taking antiplatelet medications?<\/jats:p><\/jats:sec><jats:sec id=\"S1481803518004220_abs2\" sec-type=\"general\"><jats:title>Article chosen<\/jats:title><jats:p>Zahed R, Jayazeri M, Naderi A, et al. Topical tranexamic acid compared with anterior nasal packing for treatment of epistaxis in patients taking antiplatelet drugs: randomized controlled trial. <jats:italic>Acad Emerg Med<\/jats:italic> 2018;25(3):261-6.<\/jats:p><\/jats:sec><jats:sec id=\"S1481803518004220_abs3\" sec-type=\"objectives\"><jats:title>Objectives<\/jats:title><jats:p>The primary outcome of this randomized controlled trial was the percentage of patients whose epistaxis had stopped at 10 minutes from the time of intervention. Secondary outcomes included the frequency of epistaxis recurrence at both 24 hours and 7 days, emergency department length of stay, and patient satisfaction.<\/jats:p><\/jats:sec>","DOI":"10.1017\/cem.2018.422","type":"journal-article","created":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T05:51:26Z","timestamp":1536817886000},"page":"774-776","source":"Crossref","is-referenced-by-count":4,"title":["Topical tranexamic acid for the treatment of epistaxis in patients using antiplatelet agents"],"prefix":"10.1007","volume":"20","author":[{"given":"Mark","family":"Sanderson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Powell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eddy","family":"Lang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,9,12]]},"reference":[{"key":"S1481803518004220_ref8","first-page":"24","article-title":"An outcomes analysis of anterior epistaxis management in the emergency department","volume":"45","author":"Newton","year":"2016","journal-title":"J Otolaryngol Head Neck Surg Le Journal d\u2019oto-rhino-laryngologie et de chirurgie cervico-faciale"},{"key":"S1481803518004220_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2013.06.043"},{"key":"S1481803518004220_ref6","unstructured":"Saeedi M . Emails sent to: Mark Sanderson. 05 February 2018."},{"key":"S1481803518004220_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2008.01.003"},{"key":"S1481803518004220_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2004.12.014"},{"key":"S1481803518004220_ref4","first-page":"CD010562","article-title":"Topical application of tranexamic acid for the reduction of bleeding","volume":"7","author":"Ker","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"S1481803518004220_ref5","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12645"},{"key":"S1481803518004220_ref3","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215110001921"}],"container-title":["CJEM"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1481803518004220","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T23:49:31Z","timestamp":1609458571000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1481803518004220\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S1481803518004220"],"URL":"https:\/\/doi.org\/10.1017\/cem.2018.422","relation":{},"ISSN":["1481-8035","1481-8043"],"issn-type":[{"value":"1481-8035","type":"print"},{"value":"1481-8043","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9]]}}}