{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T05:46:34Z","timestamp":1771652794353,"version":"3.50.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T00:00:00Z","timestamp":1591660800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CJEM"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec id=\"S1481803520003784_sec_a1\"><jats:title>Objectives<\/jats:title><jats:p>Vomiting is common in children after minor head injury. In previous research, isolated vomiting was not a significant predictor of intracranial injury after minor head injury; however, the significance of recurrent vomiting is unclear. This study aimed to determine the value of recurrent vomiting in predicting intracranial injury after pediatric minor head injury.<\/jats:p><\/jats:sec><jats:sec id=\"S1481803520003784_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>This secondary analysis of the CATCH2 prospective multicenter cohort study included participants (0\u201316 years) who presented to a pediatric emergency department (ED) within 24 hours of a minor head injury. ED physicians completed standardized clinical assessments. Recurrent vomiting was defined as \u2265 four episodes. Intracranial injury was defined as acute intracranial injury on computed tomography scan. Predictors were examined using chi-squared tests and logistic regression models.<\/jats:p><\/jats:sec><jats:sec id=\"S1481803520003784_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>A total of 855 (21.1%) of the 4,054 CATCH2 participants had recurrent vomiting, 197 (4.9%) had intracranial injury, and 23 (0.6%) required neurosurgical intervention. Children with recurrent vomiting were significantly more likely to have intracranial injury (odds ratio [OR], 2.3; 95% confidence interval [CI], 1.7\u20133.1), and require neurosurgical intervention (OR, 3.5; 95% CI, 1.5\u20137.9). Recurrent vomiting remained a significant predictor of intracranial injury (OR, 2.8; 95% CI, 1.9\u20133.9) when controlling for other CATCH2 criteria. The probability of intracranial injury increased with number of vomiting episodes, especially when accompanied by other high-risk factors, including signs of a skull fracture, or irritability and Glasgow Coma Scale score &lt; 15 at 2 hours postinjury. Timing of first vomiting episode, and age were not significant predictors.<\/jats:p><\/jats:sec><jats:sec id=\"S1481803520003784_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>Recurrent vomiting (\u2265 four episodes) was a significant risk factor for intracranial injury in children after minor head injury. The probability of intracranial injury increased with the number of vomiting episodes and if accompanied by other high-risk factors, such as signs of a skull fracture or altered level of consciousness.<\/jats:p><\/jats:sec>","DOI":"10.1017\/cem.2020.378","type":"journal-article","created":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T02:43:15Z","timestamp":1591670595000},"page":"793-801","source":"Crossref","is-referenced-by-count":5,"title":["Characteristics of vomiting as a predictor of intracranial injury in pediatric minor head injury"],"prefix":"10.1007","volume":"22","author":[{"given":"Jessica A.","family":"Harper","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terry 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