{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T22:06:22Z","timestamp":1776377182567,"version":"3.51.2"},"reference-count":38,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2017,12,10]],"date-time":"2017-12-10T00:00:00Z","timestamp":1512864000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Neurol. Sci."],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic><jats:bold>Introduction:<\/jats:bold><\/jats:italic> In an effort to better understand why cognitively normal patients were referred to a memory clinic, we sought to identify features of \u201cworried well\u201d patients to better identify those more likely to be cognitively normal. <jats:italic><jats:bold>Methods:<\/jats:bold><\/jats:italic> In total, 375 consecutive patients referred by primary care practitioners to a Rural and Remote Memory Clinic were categorized into two groups based on their neurologic diagnosis, \u201cworried well\u201d (cognitively normal, N=81) or \u201cother\u201d (patients with any neurologic diagnosis, N=294). Data collected included: age, sex, years of formal education, Mini-Mental Status Examination score from initial visit, Center for Epidemiologic Studies Depression Scale score, Self-Rating of Memory Scale, alcohol consumption, marital status, hours per week of work, past medical history, sleep concerns, and family history of memory concerns. The two groups were compared using <jats:italic>t<\/jats:italic>-tests and \u03c7<jats:sup>2<\/jats:sup> tests. The same comparison was done between the same set of \u201cworried well\u201d patients (cognitively normal, N=81) and the subgroup of patients with a diagnosis of Alzheimer\u2019s disease (N=146) from the \u201cother\u201d group. <jats:italic><jats:bold>Results:<\/jats:bold><\/jats:italic> Significant differences included younger age, more formal education, more frequently having previous psychiatric diagnosis and more self-reported alcohol consumption in the \u201cworried well\u201d group. The \u201cworried well\u201d and \u201cAlzheimer\u2019s disease\u201d comparison had the same significant differences as the \u201cworried well\u201d and \u201cother\u201d comparison. <jats:italic><jats:bold>Conclusion:<\/jats:bold><\/jats:italic> We observed a pattern of differences unfold between the \u201cworried well\u201d patients and those with cognitive disease. No one variable was pathognomonic of a \u201cworried well\u201d patient. However, taking all the above into account when evaluating a patient may help clinically.<\/jats:p>","DOI":"10.1017\/cjn.2017.267","type":"journal-article","created":{"date-parts":[[2017,12,10]],"date-time":"2017-12-10T10:50:33Z","timestamp":1512903033000},"page":"158-167","source":"Crossref","is-referenced-by-count":17,"title":["The Worried Well? 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