{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T18:45:27Z","timestamp":1778352327683,"version":"3.51.4"},"reference-count":12,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2017,12,18]],"date-time":"2017-12-18T00:00:00Z","timestamp":1513555200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Neurol. Sci."],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This case series aimed to describe clinicoradiological, electromyographic, and etiological spectra in palatal tremor (essential=1; symptomatic=26). Patients with symptomatic palatal tremor had 2 to 10 Hz arrhythmic electromyographic bursts, a spectrum of changes in inferior olivary nucleus, with\/without lesions in Guillain Mollaret triangle, and varied etiologies (genetic=9, vascular=6, trauma=3, infections=3). Exome sequencing showed variations in <jats:italic>POLG, WDR81<\/jats:italic>, <jats:italic>NDUFS8, TENM4<\/jats:italic>, and <jats:italic>EEF2<\/jats:italic>. Clinical phenotypes of patients with <jats:italic>POLG<\/jats:italic>, <jats:italic>WDR81<\/jats:italic>, and <jats:italic>NDUFS8<\/jats:italic> variations were consistent with that described in literature. We highlight salient magnetic resonance imaging features, electrophysiological observations, and diverse etiologies in a large cohort of palatal tremor.<\/jats:p>","DOI":"10.1017\/cjn.2017.273","type":"journal-article","created":{"date-parts":[[2017,12,18]],"date-time":"2017-12-18T07:24:16Z","timestamp":1513581856000},"page":"243-247","source":"Crossref","is-referenced-by-count":9,"title":["Palatal Tremor Revisited: Disorder with Nosological Diversity and Etiological Heterogeneity"],"prefix":"10.1017","volume":"45","author":[{"given":"Madhu","family":"Nagappa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parayil S.","family":"Bindu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjib","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rose D.","family":"Bharath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mangalore","family":"Sandhya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jitender","family":"Saini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavagada S.","family":"Mathuranath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arun B.","family":"Taly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2017,12,18]]},"reference":[{"key":"S0317167117002736_ref11","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000033795.17156.00"},{"key":"S0317167117002736_ref2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh137"},{"key":"S0317167117002736_ref3","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.12195"},{"key":"S0317167117002736_ref4","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20130478"},{"key":"S0317167117002736_ref5","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e32835c60e6"},{"key":"S0317167117002736_ref6","doi-asserted-by":"publisher","DOI":"10.1007\/BF00697000"},{"key":"S0317167117002736_ref7","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000258665.37827.f6"},{"key":"S0317167117002736_ref9","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.8.1305"},{"key":"S0317167117002736_ref10","doi-asserted-by":"publisher","DOI":"10.1111\/jon.12118"},{"key":"S0317167117002736_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.mito.2016.11.002"},{"key":"S0317167117002736_ref1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/113.6.1645"},{"key":"S0317167117002736_ref8","doi-asserted-by":"publisher","DOI":"10.1111\/jon.12267"}],"container-title":["Canadian Journal of Neurological Sciences \/ Journal Canadien des Sciences Neurologiques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0317167117002736","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T19:14:56Z","timestamp":1555355696000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0317167117002736\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,18]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["S0317167117002736"],"URL":"https:\/\/doi.org\/10.1017\/cjn.2017.273","relation":{},"ISSN":["0317-1671","2057-0155"],"issn-type":[{"value":"0317-1671","type":"print"},{"value":"2057-0155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,18]]}}}