{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T22:27:54Z","timestamp":1767220074990},"reference-count":26,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T00:00:00Z","timestamp":1602806400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Neurol. Sci."],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>ABSTRACT:<\/jats:title><jats:sec id=\"S0317167120002267_as1\"><jats:title>Background:<\/jats:title><jats:p>Patients with sellar masses undergoing transsphenoidal surgery (TSS) frequently develop endocrine dysfunction; therefore, in-hospital endocrinology consultation (IHEC) is recommended. However, we wondered whether routine endocrinology assessment of all TSS patients is always necessary.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167120002267_as2\"><jats:title>Methods:<\/jats:title><jats:p>We developed an IHEC Physician\u2019s Guide to identify patients who would require peri-operative IHEC. An analysis of all patients undergoing TSS for a sellar mass over a 4-year period was conducted to assess the predictive value of the IHEC Physician\u2019s Guide in identifying patients who required IHEC.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167120002267_as3\"><jats:title>Results:<\/jats:title><jats:p>A total of 116 patients underwent TSS; 24 required IHEC. As expected, the risk of endocrine complications requiring peri-operative endocrine management was significantly higher in the IHEC group versus no-IHEC group (96% vs. 1%; <jats:italic>p<\/jats:italic> &lt; 0.001). The negative predictive value of the IHEC Physician\u2019s Guide in identifying patients who did not require IHEC was 0.99 (95% CI 0.9409\u20130.9997); Fisher\u2019s exact test, <jats:italic>p<\/jats:italic> &lt; 0.001), meaning that the IHEC Physician\u2019s Guide successfully identified all but one patient who truly required IHEC.<\/jats:p><\/jats:sec><jats:sec id=\"S0317167120002267_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>Results from our study show that most patients do not need IHEC after TSS and that those patients requiring IHEC can be reliably predicted at surgery by using a simple IHEC Physician\u2019s Guide.<\/jats:p><\/jats:sec>","DOI":"10.1017\/cjn.2020.226","type":"journal-article","created":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T06:48:34Z","timestamp":1602830914000},"page":"534-539","source":"Crossref","is-referenced-by-count":1,"title":["In-Hospital Endocrinology Consultation After Transsphenoidal Surgery: Is It Always 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