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While the organic form (methylmercury (meHg)) led to the Minamata incidence in Japan and \u201cwonder-wheat\u201d disaster in Iraq, the \u201cmad hatters\u201d and \u201cDanbury shakes\u201d were related to the inorganic elemental form (Hg vapor). Human exposure to toxic Hg continues in the modern world to a large extent by artisanal gold mining, biomass combustion, chloralkali production, and indigenous medicine use to name a few. Heavy industrial use of Hg contaminates air and landfills, affecting the aquatic ecosystem and marine food chain. A detailed social and occupational history with a high index of clinical suspicion is required to not miss this toxic etiology for movement disorders like ataxia, tremor, or myoclonus. In this review, we have discussed the past and present global health impact of Hg from a movement disorder perspective. The connection of Hg with neurodegeneration and autoimmunity has been highlighted. We have also discussed the role of chelating agents and the preventive strategies to combat the neurotoxic effects of Hg in the modern world.<\/jats:p>","DOI":"10.1017\/cjn.2021.146","type":"journal-article","created":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T07:39:53Z","timestamp":1624520393000},"page":"493-501","source":"Crossref","is-referenced-by-count":29,"title":["Mercury and Movement Disorders: The Toxic Legacy 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