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First, there are variants, an apperceptive type linked to damage to the inferior occipitotemporal cortex and an amnestic type associated with anterior temporal lesions, both either right or bilateral. Second, these variants are clustered in syndromes with other perceptual deficits, the apperceptive type with field defects, dyschromatopsia and topographagnosia, and the amnestic type with topographagnosia and the auditory disorders of phonagnosia and acquired amusia. Third, extensive testing often shows additional problems with recognizing exemplars of other objects, especially when degrees of expertise are taken into account. Fourth, the prosopagnosic impairment does not affect all facial information. For example, the perception of expression and lip-reading likely depends on other neural substrates than those for processing facial identity. Last, face perception in prosopagnosia is not immutable but can improve with extensive training, though as yet this does not represent a cure for the condition. Continuing work with neural networks and animal models will enhance our understanding of this intriguing condition and what it tells us about how our brains process vision.<\/jats:p>","DOI":"10.1017\/cjn.2024.295","type":"journal-article","created":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T08:27:02Z","timestamp":1728635222000},"page":"1-9","source":"Crossref","is-referenced-by-count":1,"title":["The 2024 Richardson Lecture: Prosopagnosia \u2013 A Classic Neurologic Deficit Meets the Modern Era"],"prefix":"10.1017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8264-3795","authenticated-orcid":false,"given":"Jason 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