{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:59:25Z","timestamp":1785419965059,"version":"3.56.0"},"reference-count":32,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Neurol. Sci."],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec id=\"S0317167126105332_as1\">\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>This study aims to evaluate differences in healthcare utilization among patients with ischemic stroke in metropolitan versus non-metropolitan Manitoba.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0317167126105332_as2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This study is a population-level analysis using the Discharge Abstract Database from Manitoba. The database includes all patients who received care in a Manitoba facility for ischemic stroke between April 2019 and March 2023. Data were collected on patient demographics, comorbidities and geographical location of stroke presentation (metropolitan Winnipeg vs non-metropolitan). Outcomes included length of stay (LOS), treatment, discharge disposition and mortality. Regression analysis was performed to analyze outcomes, adjusting for age, sex and comorbidities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0317167126105332_as3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      3704 (71.6%) patients were admitted in Winnipeg, and 1471 (28.4%) patients were admitted in non-metropolitan Manitoba. Patients presenting to Winnipeg were younger (mean age 72.3 vs 74.3 years) and had higher rates of atrial fibrillation, hypertension, diabetes, chronic kidney disease and heart failure. Patients presenting to Winnipeg had a shorter LOS (16.1 days vs 18.4 days, coefficient 0.05, 95% CI \u22124.54 to \u22121.27), had higher rates of intravenous thrombolysis (adjOR 5.13, 95% CI 3.85\u20136.84), were less likely to be discharged home (39.8% vs 57.5%, adjOR 0.47, 95% CI 0.41\u20130.53) and were more likely to be transferred for inpatient stroke rehabilitation (adjOR 3.46, 95% CI 2.64\u20134.54). There were no differences in in-hospital mortality. There was a higher incidence of stroke in Winnipeg compared to non-metropolitan Manitoba (\n                      <jats:italic>F<\/jats:italic>\n                      -statistic 23.84,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.0028).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0317167126105332_as4\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This study illustrates differences in healthcare utilization outcomes between patients living in metropolitan Winnipeg versus non-metropolitan Manitoba presenting with ischemic stroke.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/cjn.2026.10533","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T05:17:23Z","timestamp":1768886243000},"page":"1-7","source":"Crossref","is-referenced-by-count":1,"title":["Geographic Differences in Healthcare Utilization Outcomes in Ischemic Stroke: A Population-Level Study from Manitoba"],"prefix":"10.1017","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-4395-7156","authenticated-orcid":false,"given":"Angela","family":"Buchel","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gfys938","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5228-6376","authenticated-orcid":false,"given":"Anwer Zohaib","family":"Siddiqi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gfys938","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esseddeeg","family":"Ghrooda","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gfys938","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anurag","family":"Trivedi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gfys938","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4898-8495","authenticated-orcid":false,"given":"Ankur","family":"Wadhwa","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gfys938","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Candale-Radu","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gfys938","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1404-4496","authenticated-orcid":false,"given":"Radhika","family":"Kadangot","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gfys938","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babawale","family":"Arabambi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gfys938","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chetan","family":"Vekhande","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gfys938","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveed","family":"Akhtar","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gfys938","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nima","family":"Kashani","sequence":"additional","affiliation":[{"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishita","family":"Singh","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gfys938","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"S0317167126105332_ref28","doi-asserted-by":"publisher","DOI":"10.1177\/1747493020929964"},{"key":"S0317167126105332_ref18","unstructured":"18. Canadian Stroke Best Practices. Canadian Stroke Best Practices: Acute Ischemic Stroke Treatment. 2022. Accessed June 25, 2025. https:\/\/www.strokebestpractices.ca\/en\/recommendations\/acute-stroke-management\/acute-ischemic-stroke-treatment\/."},{"key":"S0317167126105332_ref4","article-title":"Stroke rehabilitation: from diagnosis to therapy","volume":"15","author":"Li","year":"2024","journal-title":"Front Neurol"},{"key":"S0317167126105332_ref30","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.121.037376"},{"key":"S0317167126105332_ref2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.123.044267"},{"key":"S0317167126105332_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2018.12.021"},{"key":"S0317167126105332_ref6","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.001938"},{"key":"S0317167126105332_ref13","doi-asserted-by":"publisher","DOI":"10.1017\/cjn.2021.35"},{"key":"S0317167126105332_ref21","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58091185"},{"key":"S0317167126105332_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2016.02.019"},{"key":"S0317167126105332_ref19","doi-asserted-by":"publisher","DOI":"10.9778\/cmajo.20160166"},{"key":"S0317167126105332_ref31","doi-asserted-by":"publisher","DOI":"10.1017\/cjn.2025.10460"},{"key":"S0317167126105332_ref32","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare8020112"},{"key":"S0317167126105332_ref22","doi-asserted-by":"publisher","DOI":"10.1017\/cjn.2015.324"},{"key":"S0317167126105332_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60584-5"},{"key":"S0317167126105332_ref27","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.170999"},{"key":"S0317167126105332_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2023.10.007"},{"key":"S0317167126105332_ref8","doi-asserted-by":"publisher","DOI":"10.5888\/pcd22.240429"},{"key":"S0317167126105332_ref9","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.124.048251"},{"key":"S0317167126105332_ref26","doi-asserted-by":"publisher","DOI":"10.3171\/2013.11.FOCUS13428"},{"key":"S0317167126105332_ref1","doi-asserted-by":"publisher","DOI":"10.1017\/cjn.2022.338"},{"key":"S0317167126105332_ref29","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.26345"},{"key":"S0317167126105332_ref14","unstructured":"14. 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