{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T02:31:54Z","timestamp":1788489114500,"version":"build-2803163510"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T00:00:00Z","timestamp":1782259200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Neurol. Sci."],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec id=\"S0317167126106325_as1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Portable ultra-low field MRI (ULF-MRI) has garnered significant attention in neuroimaging due to the high costs and accessibility issues associated with conventional high-field MRI (HF-MRI). This systematic review aims to explore the cost implications, safety issues and diagnostic capacity of ULF-MRI compared to HF-MRI in brain imaging while also examining its feasibility, limitations and challenges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0317167126106325_as2\">\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>This systematic review followed Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. A comprehensive search was conducted across four databases: Medline, Embase, Scopus and the Global Health database. Additionally, the reference lists of studies identified through the database searches were examined. Studies were included if they involved brain imaging with ULF-MRI, used HF-MRI as a comparator and reported on costs, diagnostic accuracy, safety and\/or feasibility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0317167126106325_as3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>ULF-MRI has shown feasibility and applicability in diverse settings, including emergency departments, intensive care units and remote healthcare centres. Diagnostic capabilities have demonstrated good concordance with HF-MRI for various conditions, such as stroke (90% accuracy for ischaemic infarcts), multiple sclerosis (94% detection of lesions) and intracerebral haemorrhage (80.4\u201392.1% sensitivity). Challenges of ULF-MRI include a reduced signal-to-noise ratio and lower resolution, which can affect image quality and the detection of subtle lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0317167126106325_as4\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>While ULF-MRI has shown promising diagnostic accuracy for various neurological conditions, its lower image resolution limits the detection of subtle lesions, and it cannot yet replace HF-MRI. Continued technical advancements and further research are needed to improve image quality and promote broader clinical adoption.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/cjn.2026.10632","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T07:54:10Z","timestamp":1782287650000},"page":"1-10","source":"Crossref","is-referenced-by-count":1,"title":["Diagnostic Efficacy, Costs and Safety of Portable Ultra-Low Field MRI in Brain Imaging: A Systematic Review"],"prefix":"10.1017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7704-1746","authenticated-orcid":false,"given":"Gebeyehu Begashaw","family":"Abate","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0220mzb33","id-type":"ROR","asserted-by":"publisher"}],"name":"King\u2019s College London"},{"name":"University of Gondar"},{"name":"King\u2019s College London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Giampietro","sequence":"additional","affiliation":[{"name":"King\u2019s College London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niall","family":"Bourke","sequence":"additional","affiliation":[{"name":"King\u2019s College London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carly","family":"Bennallick","sequence":"additional","affiliation":[{"name":"King\u2019s College London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Williams","sequence":"additional","affiliation":[{"name":"King\u2019s College London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0194-7250","authenticated-orcid":false,"given":"Ricardo","family":"Twumasi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0220mzb33","id-type":"ROR","asserted-by":"publisher"}],"name":"King\u2019s College London"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,6,24]]},"container-title":["Canadian Journal of Neurological Sciences \/ Journal Canadien des Sciences Neurologiques"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0317167126106325","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T07:37:11Z","timestamp":1784533031000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0317167126106325\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,24]]},"references-count":0,"alternative-id":["S0317167126106325"],"URL":"https:\/\/doi.org\/10.1017\/cjn.2026.10632","relation":{},"ISSN":["0317-1671","2057-0155"],"issn-type":[{"value":"0317-1671","type":"print"},{"value":"2057-0155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,24]]}}}