{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T07:07:30Z","timestamp":1774076850817,"version":"3.50.1"},"reference-count":32,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"unspecified","delay-in-days":117,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Trans. Sci."],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:sec id=\"S2059866125000779_as1\">\n\t    <jats:title>Introduction:<\/jats:title>\n\t    <jats:p>Guideline-based tobacco treatment is infrequently offered. Electronic health record-enabled patient-generated health data (PGHD) has the potential to increase patient treatment engagement and satisfaction.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2059866125000779_as2\">\n\t    <jats:title>Methods:<\/jats:title>\n\t    <jats:p>We evaluated outcomes of a strategy to enable PGHD in a medical oncology clinic from July 1, 2021 to December 31, 2022. Among 12,777 patients, 82.1% received a tobacco screener about use and interest in treatment as part of eCheck-in via the patient portal.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2059866125000779_as3\">\n\t    <jats:title>Results:<\/jats:title>\n\t    <jats:p>We attained a broad reach (82.1%) and moderate response rate (30.9%) for this low-burden PGHD strategy. Patients reporting current smoking (<jats:italic>n<\/jats:italic> = 240) expressed interest in smoking cessation medication (47.9%) and counseling (35.8%). As a result of patient requests via PGHD, most tobacco treatment requests by patients were addressed by their providers (40.6\u201380.3%). Among patients with active smoking, those who received\/answered the screener (<jats:italic>n<\/jats:italic> = 309 ) were more likely to receive tobacco treatment compared with usual care patients who did not have the patient portal (<jats:italic>n<\/jats:italic> = 323) (OR = 2.72, 95% CI = 1.93\u20133.82, <jats:italic>P<\/jats:italic> &lt; 0.0001) using propensity scores to adjust for the effect of age, sex, race, insurance, and comorbidity. Patients who received yet ignored the screener (<jats:italic>n<\/jats:italic> = 1024) compared with usual care were also more likely to receive tobacco treatment, but to a lesser extent (OR = 2.20, 95% CI = 1.68\u20132.86, <jats:italic>P<\/jats:italic> &lt; 0.0001). We mapped observed and potential benefits to the Translational Science Benefits Model (TSBM).<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2059866125000779_as4\">\n\t    <jats:title>Discussion:<\/jats:title>\n\t    <jats:p>PGHD via patient portal appears to be a feasible, acceptable, scalable, and cost-effective approach to promote patient-centered care and tobacco treatment in cancer patients. Importantly, the PGHD approach serves as a real world example of cancer prevention leveraging the TSBM.<\/jats:p>\n\t  <\/jats:sec>","DOI":"10.1017\/cts.2025.77","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:31:02Z","timestamp":1745800262000},"source":"Crossref","is-referenced-by-count":1,"title":["Patient-generated health data: Impact on promoting patient-centered point of care tobacco treatment in patients with cancer"],"prefix":"10.1017","volume":"9","author":[{"given":"Jessica","family":"Liu","sequence":"first","affiliation":[{"name":"Washington State University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy B.","family":"Baker","sequence":"additional","affiliation":[{"name":"University of Wisconsin School of Medicine and Public Health"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingling","family":"Chen","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Smock","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas B.","family":"Griffith","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramaswamy","family":"Govindan","sequence":"additional","affiliation":[{"name":"Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine"},{"name":"Washington University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Goldberg","sequence":"additional","affiliation":[{"name":"Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine"},{"name":"Washington University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jodi","family":"Thole","sequence":"additional","affiliation":[{"name":"Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine"},{"name":"Washington University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristin","family":"Daly","sequence":"additional","affiliation":[{"name":"Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine"},{"name":"Washington University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Reddy","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3471-3725","authenticated-orcid":false,"given":"Alex T.","family":"Ramsey","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine"},{"name":"Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura J.","family":"Bierut","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine"},{"name":"Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aimee","family":"James","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Schnoll","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ross C.","family":"Brownson","sequence":"additional","affiliation":[{"name":"Brown School at Washington University in St. Louis"},{"name":"Washington University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6762-5054","authenticated-orcid":false,"given":"Li-Shiun","family":"Chen","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine"},{"name":"Alvin J. 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Smoking and tobacco use 2021, https:\/\/www.cdc.gov\/tobacco\/patient-care\/care-settings\/cancer\/index.htm."},{"key":"S2059866125000779_ref23","first-page":"182","article-title":"Innovations in research and clinical care using patient-generated health data","volume":"70","author":"Jim","year":"2020","journal-title":"CA Cancer J Clin"},{"key":"S2059866125000779_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmonc.2012.10.003"},{"key":"S2059866125000779_ref26","doi-asserted-by":"publisher","DOI":"10.1111\/cts.12495"},{"key":"S2059866125000779_ref11","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2011-0169"},{"key":"S2059866125000779_ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-019-00787-5"},{"key":"S2059866125000779_ref22","volume-title":"Digital Health","author":"Mars","year":"2022"},{"key":"S2059866125000779_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2023.10.011"},{"key":"S2059866125000779_ref18","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2018-0246"},{"key":"S2059866125000779_ref20","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-018-5119-0"},{"key":"S2059866125000779_ref1","unstructured":"1. Centers for Disease Control and Prevention (US); National Center for Chronic Disease Prevention and Health Promotion (US); Office on Smoking and Health (US). How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease: A Report of the Surgeon General. Atlanta (GA): Centers for Disease Control and Prevention (US); 2010. 5, Cancer. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK53010\/."},{"key":"S2059866125000779_ref9","unstructured":"9. ASCO (American Society of Clinical Oncology). Stop Tobacco Use After a Cancer Diagnosis: Resources and Guidance for Patients and Families from the American Society of Clinical Oncology. 2019. Accessed on 1\/31\/2024 https:\/\/www.cancer.net\/sites\/cancer.net\/files\/stopping_tobacco_use.pdf."},{"key":"S2059866125000779_ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2021.07.019"},{"key":"S2059866125000779_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2020.11.001"},{"key":"S2059866125000779_ref27","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17051728"},{"key":"S2059866125000779_ref29","doi-asserted-by":"publisher","DOI":"10.1093\/jamiaopen\/ooz061"},{"key":"S2059866125000779_ref32","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.3.732"},{"key":"S2059866125000779_ref30","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-021-06626-7"},{"key":"S2059866125000779_ref3"},{"key":"S2059866125000779_ref6","volume-title":"Treating Smoking in Cancer Patients: An Essential Component of Cancer Care. National Cancer Institute Tobacco Control Monograph 23","year":"2022"},{"key":"S2059866125000779_ref2","unstructured":"2. Centers for Disease Control and Prevention. National Center for Chronic Disease Prevention and Health Promotion. 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