{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T10:36:48Z","timestamp":1784889408038,"version":"3.55.0"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2016,2,26]],"date-time":"2016-02-26T00:00:00Z","timestamp":1456444800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Disaster med. public health prep."],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1935789315001858_abs1\" sec-type=\"general\"><jats:title>Objective<\/jats:title><jats:p>To determine dynamic changes in clinical characteristics by examining an outbreak of adenovirus infection that occurred from December 20, 2012, to February 25, 2013, in Tianjin, China.<\/jats:p><\/jats:sec><jats:sec id=\"S1935789315001858_abs2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>Active surveillance for febrile respiratory illnesses was conducted, and medical records of patients were collected. Real-time quantitative polymerase chain reaction and sequencing were used for pathogen identification and viral genome study, respectively. Student\u2019s <jats:italic>t<\/jats:italic>-test was used to compare the mean values of normally distributed continuous variables. Mann-Whitney U or Kruskal-Wallis tests were used if continuous variables were not normally distributed. Pearson\u2019s chi-square test or Fisher\u2019s exact test was used to compare categorical variables.<\/jats:p><\/jats:sec><jats:sec id=\"S1935789315001858_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>The outbreak was sourced from the index case diagnosed as the common cold on December 20, 2012; a total of 856 cases were reported in the following 66 days. The pathogen was identified as human adenovirus (HAdV) 55. The symptoms manifested differently in severe and mild cases. Routine blood examinations, liver function indexes, and heart function indexes showed different dynamic patterns over time in hospitalized patients.<\/jats:p><\/jats:sec><jats:sec id=\"S1935789315001858_abs4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>Clinical characteristics and laboratory examinations may reveal unique patterns over the course of HAdV-55 infection. (<jats:italic>Disaster Med Public Health Preparedness<\/jats:italic>. 2018;12:464\u2013469)<\/jats:p><\/jats:sec>","DOI":"10.1017\/dmp.2015.185","type":"journal-article","created":{"date-parts":[[2016,2,26]],"date-time":"2016-02-26T07:38:10Z","timestamp":1456472290000},"page":"464-469","source":"Crossref","is-referenced-by-count":8,"title":["Dynamic Changes in Clinical Characteristics During an Outbreak of Human Adenovirus Serotype 55 in China"],"prefix":"10.1017","volume":"12","author":[{"given":"Hong-Wei","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mao-Ti","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao-Jun","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Quan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Zhong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Long","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-Ke","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2016,2,26]]},"reference":[{"key":"S1935789315001858_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2012.04.018"},{"key":"S1935789315001858_ref9","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20441"},{"key":"S1935789315001858_ref5","doi-asserted-by":"publisher","DOI":"10.3201\/1708.101760"},{"key":"S1935789315001858_ref1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0121375"},{"key":"S1935789315001858_ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2009.02347.x"},{"key":"S1935789315001858_ref8","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a121632"},{"key":"S1935789315001858_ref2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0042732"},{"key":"S1935789315001858_ref11","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00282-09"},{"key":"S1935789315001858_ref4","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir040"},{"key":"S1935789315001858_ref3","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01694-09"},{"key":"S1935789315001858_ref10","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01928-09"},{"key":"S1935789315001858_ref7","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01769-08"},{"key":"S1935789315001858_ref6","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv141"}],"container-title":["Disaster Medicine and Public Health Preparedness"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1935789315001858","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,13]],"date-time":"2019-04-13T22:44:47Z","timestamp":1555195487000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1935789315001858\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,26]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["S1935789315001858"],"URL":"https:\/\/doi.org\/10.1017\/dmp.2015.185","relation":{},"ISSN":["1935-7893","1938-744X"],"issn-type":[{"value":"1935-7893","type":"print"},{"value":"1938-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,26]]}}}