{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T11:42:59Z","timestamp":1792064579052,"version":"4.4.0"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T00:00:00Z","timestamp":1716249600000},"content-version":"unspecified","delay-in-days":141,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Disaster med. public health prep."],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:sec id=\"S1935789324001083_as1\">\n\t    <jats:title>Objective:<\/jats:title>\n\t    <jats:p>Cancer patients are among the most vulnerable populations during and after a disaster. We evaluated the impact of treatment interruption on the survival of women with gynecologic cancer in Puerto Rico following Hurricanes Irma and Mar\u00eda.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S1935789324001083_as2\">\n\t    <jats:title>Methods:<\/jats:title>\n\t    <jats:p>A retrospective cohort study among a clinic-based sample of women with gynecological cancer diagnosed between January 2016 and September 2017 (n = 112) was done. Women were followed from their diagnosis until December 2019, to assess vital status. Kaplan-Meier survival curves and Cox proportional hazards models were performed.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S1935789324001083_as3\">\n\t    <jats:title>Results:<\/jats:title>\n\t    <jats:p>Mean age was 56 (\u00b1 12.3) years; corpus uteri (58.9%) was the most common gynecologic cancer. Predominant treatments were surgery (91.1%) and chemotherapy (44.6%). Overall, 75.9% were receiving treatment before the hurricanes, 16.1% experienced treatment interruptions, and 8.9% died during the follow-up period. Factors associated with treatment interruption in bivariate analysis included younger age (\u226455 years), having regional\/distant disease, and receiving &gt; 1 cancer treatment (<jats:italic>P<\/jats:italic> &lt; 0.05). Crude analysis revealed an increased risk of death among women with treatment interruption (HR: 3.88, 95% CI: 1.09-13.77), persisting after adjusting for age and cancer stage (HR: 2.49, 95% CI: 0.69-9.01).<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S1935789324001083_as4\">\n\t    <jats:title>Conclusions:<\/jats:title>\n\t    <jats:p>Findings underscore the detrimental impact of treatment interruption on cancer survival in the aftermath of hurricanes, emphasizing the need for emergency response plans for this vulnerable population.<\/jats:p>\n\t  <\/jats:sec>","DOI":"10.1017\/dmp.2024.108","type":"journal-article","created":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T08:06:14Z","timestamp":1716278774000},"source":"Crossref","is-referenced-by-count":9,"title":["Treatment Interruptions and Mortality Among Puerto Rican Women With Gynecologic Cancers in Puerto Rico After Hurricanes Irma and Mar\u00eda: A Retrospective Cohort Study"],"prefix":"10.1017","volume":"18","author":[{"given":"Fabiola A.","family":"Rivera-Gast\u00f3n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharee","family":"Umpierre-Catinchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeslie M.","family":"Ramos-Cartagena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen J.","family":"Ortiz-Ortiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos R.","family":"Torres-Cintr\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra I.","family":"Garc\u00eda-Camacho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Calo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Tortolero-Luna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2073-3418","authenticated-orcid":false,"given":"Liz M.","family":"Mart\u00ednez-Ocasio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1017-9473","authenticated-orcid":false,"given":"Ana P.","family":"Ortiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2024,5,21]]},"container-title":["Disaster Medicine and Public Health Preparedness"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1935789324001083","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T04:30:50Z","timestamp":1725597050000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1935789324001083\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":0,"alternative-id":["S1935789324001083"],"URL":"https:\/\/doi.org\/10.1017\/dmp.2024.108","relation":{},"ISSN":["1935-7893","1938-744X"],"issn-type":[{"value":"1935-7893","type":"print"},{"value":"1938-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]},"article-number":"e105"}}