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Therefore, this review aims to: delineate the critical golden time periods following earthquakes and identify the most effective responses and resilience factors during these periods; accurately define the terminology for injuries sustained post-earthquake; elucidate the basic pathophysiology of CRUSH injury-induced myopathy, one of the most significant pathologies in post-earthquake patient management; explore the role of nitric oxide (NO) mechanisms in crush injuries, which are believed to be fundamental to the \u201csmiling death phenomenon\u201d and represent the unseen part of the iceberg; and highlight the importance of the 3 main phenomena responsible for mortality\u2014acidosis, coagulopathy, and hypothermia\u2014during disasters. This comprehensive review, based on the latest literature, encompasses search and rescue, pre-hospital processes, emergency department procedures, and subsequent internal and surgical management algorithms.<\/jats:p>","DOI":"10.1017\/dmp.2024.253","type":"journal-article","created":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T13:37:37Z","timestamp":1730727457000},"source":"Crossref","is-referenced-by-count":10,"title":["The Pathophysiology of Injuries and Deaths Managed in Emergency Departments After Earthquake Disasters: A Narrative Review"],"prefix":"10.1017","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8166-659X","authenticated-orcid":false,"given":"Sarper","family":"Yilmaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Cankut","family":"Tatliparmak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8324-3264","authenticated-orcid":false,"given":"Rohat","family":"Ak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2024,11,4]]},"reference":[{"key":"S1935789324002532_r39","unstructured":"39. 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