{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T21:32:04Z","timestamp":1790371924607,"version":"4.1.0"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"unspecified","delay-in-days":268,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Disaster med. public health prep."],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>The war in Ukraine raises concerns for potential hazards of radiological incidents and their impact on humans, especially families. Preparedness and response to radiological and nuclear incidents necessitates familiarity with pharmaceutical countermeasures, including antidotes and cytokines. Searches found no published study comparing adult indications and dosing among standard references. This study addresses this gap by collecting, tabulating, and disseminating information to health care professionals. Expert consensus chose the following references to compare adult indications and dosing of medical countermeasures for radiation exposure and internal contamination with radioactive materials: <jats:italic>Advanced Hazmat Life Support (AHLS) for Radiological Incidents &amp; Terrorism<\/jats:italic>, <jats:italic>DailyMed<\/jats:italic>, <jats:italic>Internal Contamination Clinical Reference<\/jats:italic>, <jats:italic>Medical Aspects of Radiation Incidents<\/jats:italic>, <jats:italic>Medical Management of Radiological Casualties<\/jats:italic>, <jats:italic>Micromedex<\/jats:italic>, <jats:italic>National Stockpiles for Radiological and Nuclear Emergencies: Policy Advice<\/jats:italic>, <jats:italic>POISINDEX<\/jats:italic>, and <jats:italic>Radiation Emergency Medical Management (REMM).<\/jats:italic> This is the first study comparing adult indications and dosing for medical countermeasures among common references for radiological and nuclear incidents.<\/jats:p>","DOI":"10.1017\/dmp.2025.10190","type":"journal-article","created":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T05:19:02Z","timestamp":1758863942000},"source":"Crossref","is-referenced-by-count":1,"title":["Adult Medical Countermeasures: Antidotes and Cytokines for Radiological and Nuclear Incidents and Terrorism"],"prefix":"10.1017","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9950-4863","authenticated-orcid":false,"given":"Thom","family":"Maciulewicz","sequence":"first","affiliation":[{"name":"University of Arizona"},{"name":"University of Arizona"},{"name":"Western Regional Alliance for Pediatric Emergency Management (WRAP-EM)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziad","family":"Kazzi","sequence":"additional","affiliation":[{"name":"Western Regional Alliance for Pediatric Emergency Management (WRAP-EM)"},{"name":"Emory University School of Medicine"},{"name":"Southern Regional Disaster Response System"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Navis","sequence":"additional","affiliation":[{"name":"Western Regional Alliance for Pediatric Emergency Management (WRAP-EM)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Blomquist","sequence":"additional","affiliation":[{"name":"Western Regional Alliance for Pediatric Emergency Management (WRAP-EM)"},{"name":"Banner University Medical Center South"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodore J.","family":"Cieslak","sequence":"additional","affiliation":[{"name":"Western Regional Alliance for Pediatric Emergency Management (WRAP-EM)"},{"name":"University of Nebraska Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doneen J.","family":"West","sequence":"additional","affiliation":[{"name":"Western Regional Alliance for Pediatric Emergency Management (WRAP-EM)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Newton","sequence":"additional","affiliation":[{"name":"Western Regional Alliance for Pediatric Emergency Management (WRAP-EM)"},{"name":"University of California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Lin","sequence":"additional","affiliation":[{"name":"Western Regional Alliance for Pediatric Emergency Management (WRAP-EM)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Nelsen","sequence":"additional","affiliation":[{"name":"Western Regional Alliance for Pediatric Emergency Management (WRAP-EM)"},{"name":"Intermountain Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2684-0851","authenticated-orcid":false,"given":"Frank G.","family":"Walter","sequence":"additional","affiliation":[{"name":"University of Arizona"},{"name":"University of Arizona"},{"name":"Western Regional Alliance for Pediatric Emergency Management (WRAP-EM)"},{"name":"Arizona Department of Health Services (ADHS)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,9,26]]},"reference":[{"key":"S1935789325101900_r1","unstructured":"1. United States Government Accountability Office; National Preparedness: Efforts to Address the Medical Needs of Children in a Chemical, Biological, Radiological, or Nuclear Incident. 2013:1\u201339. https:\/\/www.gao.gov\/assets\/gao-13-438.pdf."},{"key":"S1935789325101900_r5","first-page":"6","article-title":"Children and families in the context of disasters: Implications for preparedness and response","volume":"24","author":"Pfefferbaum","year":"2008","journal-title":"Fam Psychol."},{"key":"S1935789325101900_r3","volume-title":"Public Health and Preventive Medicine","author":"Cieslak","year":"2008"},{"key":"S1935789325101900_r14","unstructured":"14. U.S. Department of Health & Human Services, Administration for Strategic Preparedness and Response, Radiation Emergency Medical Management (REMM), Radiation Countermeasures for Treatment of Internal Radiation Contamination. Updated May 3, 2024. Accessed May 14, 2024. Available at: https:\/\/remm.hhs.gov\/int_contamination.htm#blockingagents."},{"key":"S1935789325101900_r13","unstructured":"13. Ionizing radiation. In Depth Answers. POISINDEX\u00ae System (electronic version). Merative, Ann Arbor, MI, USA. Updated November 6, 2021. Accessed May 1, 2023. Available at: https:\/\/www.micromedexsolutions.com\/micromedex2\/librarian\/CS\/644AFB\/ND_PR\/evidencexpert\/ND_P\/evidencexpert\/DUPLICATIONSHIELDSYNC\/A3E7E2\/ND_PG\/evidencexpert\/ND_B\/evidencexpert\/ND_AppProduct\/evidencexpert\/ND_T\/evidencexpert\/PFActionId\/evidencexpert.DoIntegratedSearch?SearchTerm=ionizing%20radiation&UserSearchTerm=ionizing%20radiation&SearchFilter=filterNone&navitem=searchALL#"},{"key":"S1935789325101900_r7"},{"key":"S1935789325101900_r12","unstructured":"12. National stockpiles for radiological and nuclear emergencies: policy advice. Geneva: World Health Organization; 2023. License: CC BY-NC-SA 3.0 IGO."},{"key":"S1935789325101900_r11","unstructured":"11. MerativeTM Micromedex\u00ae DRUGDEX\u00ae (electronic version). Merative, Ann Arbor, MI. Accessed May 14, 2024. Available at: https:\/\/www.micromedexsolutions.com\/."},{"key":"S1935789325101900_r8","unstructured":"8. U.S. Department of Health & Human Services, Centers for Disease Control and Prevention, and Oak Ridge Institute for Science and Education. Internal Contamination Clinical Reference (ICCR) Application. (Version 2.0.201) [Mobile app.] Updated December 3, 2021. Accessed May 14, 2024. Available from: https:\/\/www.cdc.gov\/nceh\/radiation\/emergencies\/iccr.htm via the Apple Store and Google Play."},{"key":"S1935789325101900_r9","unstructured":"9. U.S. Department of Energy, Oak Ridge Affiliated Universities, Radiation Emergency Assistance Center\/Training Site (REAC\/TS), The Medical Aspects of Radiation Incidents, 4th ed, 2017, pp 1\u201360. Accessed May 14, 2024. Available at: https:\/\/orise.orau.gov\/resources\/reacts\/documents\/medical-aspects-of-radiation-incidents.pdf."},{"key":"S1935789325101900_r4","doi-asserted-by":"publisher","DOI":"10.5334\/ijic.4189"},{"key":"S1935789325101900_r10","unstructured":"10. Armed Forces Radiobiology Research Institute (AFRI), Military Medical Operations, Bethesda, MD, Medical Management of Radiological Casualties, 4th ed, 2013, pp 1\u201352. Accessed May 14, 2024. Available at: https:\/\/afrri.usuhs.edu\/sites\/default\/files\/2020-07\/4edmmrchandbook.pdf."},{"key":"S1935789325101900_r15","unstructured":"15. National Council on Radiation Protection and Measurements (NCRP), Bethesda, MD. Management of Persons Contaminated with Radionuclides. Report No. 161 (2008)."},{"key":"S1935789325101900_r2","doi-asserted-by":"publisher","DOI":"10.1017\/dmp.2024.35"},{"key":"S1935789325101900_r6","first-page":"1","volume-title":"Advanced Hazmat Life Support for Radiological Incidents and Terrorism","author":"Kazzi","year":"2020"}],"container-title":["Disaster Medicine and Public Health Preparedness"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1935789325101900","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T05:19:06Z","timestamp":1758863946000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1935789325101900\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":15,"alternative-id":["S1935789325101900"],"URL":"https:\/\/doi.org\/10.1017\/dmp.2025.10190","relation":{},"ISSN":["1935-7893","1938-744X"],"issn-type":[{"value":"1935-7893","type":"print"},{"value":"1938-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"e278"}}