{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T10:16:44Z","timestamp":1783505804796,"version":"3.55.0"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:00:00Z","timestamp":1781049600000},"content-version":"unspecified","delay-in-days":160,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Camb. prisms Glob. ment. health"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    India\u2019s aging population faces escalating cognitive decline and neuropsychiatric challenges. This cross-sectional study examined relationships between geriatric depression, neuropsychiatric symptoms and cognitive performance among 1,013 community-dwelling elderly participants (\u226560\u00a0years) in Gorakhpur using the ICMR-MUDRA Toolbox. Multistage random sampling was employed. Depression was assessed using GDS-30, and neuropsychiatric symptoms were assessed using NPI-Brief. It was observed that geriatric depression was present in 63.3% of participants, while neuropsychiatric symptoms affected 78.5%, predominantly agitation (15%) and irritability (12%). Cognitive performance declined significantly across depression severity in attention, executive function, memory, language and visuospatial domains (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u00a00.001). Adjusted regression revealed that mild depression was negatively associated with executive function and memory, while severe depression showed stronger associations with language and visuospatial abilities. Neuropsychiatric symptoms independently impacted cognitive domains. These findings highlight the need for integrated mental health screening and early intervention strategies within routine geriatric care in India.\n                  <\/jats:p>","DOI":"10.1017\/gmh.2026.10246","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T10:26:44Z","timestamp":1781087204000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Relationship between depression, neuropsychiatric symptoms and cognitive profiles of the elderly in India: An assessment using the ICMR-MUDRA toolbox"],"prefix":"10.1017","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8059-9364","authenticated-orcid":false,"given":"U.","family":"Venkatesh","sequence":"first","affiliation":[{"name":"All India Institute of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varkey Nadakkavukaran","family":"Santhosh","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margubur","family":"Rahaman","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Om Prakash","family":"Bera","sequence":"additional","affiliation":[{"name":"Global Health Advocacy Incubator"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashoo","family":"Grover","sequence":"additional","affiliation":[{"name":"Delivery Research Division, Indian Council of Medical Research"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoj","family":"Prithviraj","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hari Shanker","family":"Joshi","sequence":"additional","affiliation":[{"name":"Indian Council of Medical Research - National Institute of Health Research"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anand Mohan","family":"Dixit","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vibha","family":"Dutta","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,6,10]]},"container-title":["Cambridge Prisms: Global Mental Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S2054425126102465","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T09:38:22Z","timestamp":1783503502000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S2054425126102465\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"alternative-id":["S2054425126102465"],"URL":"https:\/\/doi.org\/10.1017\/gmh.2026.10246","relation":{"has-review":[{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr7","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr6","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr9","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr8","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr12","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr3","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr11","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr2","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr10","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr5","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr4","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr1","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr14","asserted-by":"object"},{"id-type":"doi","id":"10.1017\/gmh.2026.10246.pr13","asserted-by":"object"}]},"ISSN":["2054-4251"],"issn-type":[{"value":"2054-4251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"\u00a9 The Author(s), 2026. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e134"}}