{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T05:22:18Z","timestamp":1778563338763,"version":"3.51.4"},"reference-count":48,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2015,5,20]],"date-time":"2015-05-20T00:00:00Z","timestamp":1432080000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec id=\"S0899823X15001166_abs1\" sec-type=\"general\"><jats:title>OBJECTIVE<\/jats:title><jats:p>Surgical site infections (SSIs) are a leading cause of morbidity and mortality among women undergoing cesarean section (C-section), a common procedure in North America. While risk factors for SSI are often modifiable, wide variation in clinical practice exists. With this review, we provide a comprehensive overview of the results and quality of systematic reviews and meta-analyses on interventions to reduce surgical site infections among women undergoing C-section.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X15001166_abs2\" sec-type=\"methods\"><jats:title>METHODS<\/jats:title><jats:p>We searched PubMed and the Cochrane Database of Systematic Reviews for systematic reviews and meta-analyses published between January 2000 and May 2014 on interventions to reduce the occurrence of SSIs (incisional infections and endometritis), among women undergoing C-section. We extracted data on the interventions, outcomes, and strength of evidence as determined by the original article authors, and assessed the quality of each article based on a modified Assessment of Multiple Systematic Reviews tool.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X15001166_abs3\" sec-type=\"results\"><jats:title>RESULTS<\/jats:title><jats:p>A total of 30 review articles met inclusion criteria and were reviewed. Among these articles, 77 distinct interventions were evaluated: 29% were supported with strong evidence as assessed by the original article authors, and 83% of the reviews articles were classified as good quality based on our assessment. Ten interventions were classified as being effective in reducing SSI with strong evidence in a good-quality article, including preoperative vaginal cleansing, the use of perioperative antibiotic prophylaxis, and several surgical techniques.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X15001166_abs4\" sec-type=\"conclusion\"><jats:title>CONCLUSION<\/jats:title><jats:p>Efforts to reduce SSI rates among women undergoing C-section should include interventions such as preoperative vaginal cleansing and the use of perioperative antibiotics because compelling evidence exists to support their effectiveness.<\/jats:p><jats:p><jats:italic>Infect Control Hosp Epidemiol<\/jats:italic> 2015;36(8):915\u2013921<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2015.116","type":"journal-article","created":{"date-parts":[[2015,5,20]],"date-time":"2015-05-20T09:45:11Z","timestamp":1432115111000},"page":"915-921","source":"Crossref","is-referenced-by-count":17,"title":["Practices to Reduce Surgical Site 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