{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T20:47:03Z","timestamp":1781815623620,"version":"3.54.5"},"reference-count":37,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2016,6,28]],"date-time":"2016-06-28T00:00:00Z","timestamp":1467072000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:sec id=\"S0899823X16001379_abs1\" sec-type=\"general\"><jats:title>OBJECTIVE<\/jats:title><jats:p>To characterize the epidemiology of bloodstream infections in Switzerland, comparing selected pathogens in community and university hospitals.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X16001379_abs2\" sec-type=\"general\"><jats:title>DESIGN<\/jats:title><jats:p>Observational, retrospective, multicenter laboratory surveillance study.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X16001379_abs3\" sec-type=\"methods\"><jats:title>METHODS<\/jats:title><jats:p>Data on bloodstream infections from 2008 through 2014 were obtained from the Swiss infection surveillance system, which is part of the Swiss Centre for Antibiotic Resistance (ANRESIS). We compared pathogen prevalences across 26 acute care hospitals. A subanalysis for community-acquired and hospital-acquired bloodstream infections in community and university hospitals was performed.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X16001379_abs4\" sec-type=\"results\"><jats:title>RESULTS<\/jats:title><jats:p>A total of 42,802 bloodstream infection episodes were analyzed. The most common etiologies were<jats:italic>Escherichia coli<\/jats:italic>(28.3%),<jats:italic>Staphylococcus aureus<\/jats:italic>(12.4%), and polymicrobial bloodstream infections (11.4%). The proportion of<jats:italic>E. coli<\/jats:italic>increased from 27.5% in 2008 to 29.6% in 2014 (<jats:italic>P<\/jats:italic>= .04).<jats:italic>E. coli<\/jats:italic>and<jats:italic>S. aureus<\/jats:italic>were more commonly reported in community than university hospitals (34.3% vs 22.7%,<jats:italic>P<\/jats:italic>&lt;.001 and 13.9% vs 11.1%,<jats:italic>P<\/jats:italic>&lt;.001, respectively). Fifty percent of episodes were community-acquired, with<jats:italic>E. coli<\/jats:italic>again being more common in community hospitals (41.0% vs 32.4%,<jats:italic>P<\/jats:italic>&lt;.001). The proportion of<jats:italic>E. coli<\/jats:italic>in community-acquired bloodstream infections increased in community hospitals only. Community-acquired polymicrobial infections (9.9% vs 5.6%,<jats:italic>P<\/jats:italic>&lt;.001) and community-acquired coagulase-negative staphylococci (6.7% vs 3.4%,<jats:italic>P<\/jats:italic>&lt;0.001) were more prevalent in university hospitals.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X16001379_abs5\" sec-type=\"conclusions\"><jats:title>CONCLUSIONS<\/jats:title><jats:p>The role of<jats:italic>E. coli<\/jats:italic>as predominant pathogen in bloodstream infections has become more pronounced. There are distinct patterns in community and university hospitals, potentially influencing empirical antibiotic treatment.<\/jats:p><jats:p><jats:italic>Infect Control Hosp Epidemiol<\/jats:italic>2016;37:1060\u20131067<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2016.137","type":"journal-article","created":{"date-parts":[[2016,6,28]],"date-time":"2016-06-28T09:10:44Z","timestamp":1467105044000},"page":"1060-1067","source":"Crossref","is-referenced-by-count":29,"title":["National Bloodstream Infection Surveillance in Switzerland 2008\u20132014: Different Patterns and Trends for University and Community Hospitals"],"prefix":"10.1017","volume":"37","author":[{"given":"Niccol\u00f2","family":"Buetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"Marschall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Atkinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Kronenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Swiss Centre for Antibiotic Resistance (ANRESIS)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2016,6,28]]},"reference":[{"key":"S0899823X16001379_ref18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2012.03845.x"},{"key":"S0899823X16001379_ref23","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12144"},{"key":"S0899823X16001379_ref6","unstructured":"European Centre for Disease Prevention and Control (ECDC). 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