{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:03:08Z","timestamp":1777384988475,"version":"3.51.4"},"reference-count":20,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T00:00:00Z","timestamp":1502323200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:sec id=\"S0899823X17001659_abs1\" sec-type=\"general\"><jats:title>OBJECTIVE<\/jats:title><jats:p>To describe the utilization of electronic medical data resources, including health records and nursing scheduling resources, to conduct a tuberculosis (TB) exposure investigation in a high-risk oncology unit.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X17001659_abs2\" sec-type=\"general\"><jats:title>SETTING<\/jats:title><jats:p>A 42-bed inpatient unit with a mix of surgical and medical patients at a large tertiary-care cancer center in New York City.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X17001659_abs3\" sec-type=\"general\"><jats:title>PARTICIPANTS<\/jats:title><jats:p>High-risk subjects and coworkers exposed to a healthcare worker (HCW) with cavitary smear positive lung TB.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X17001659_abs4\" sec-type=\"results\"><jats:title>RESULTS<\/jats:title><jats:p>During the 3-month exposure period, 270 patients were admitted to the unit; 137 of these (50.7%) received direct care from the index case HCW. Host immune status and intensity of exposure were used to establish criteria for postexposure testing, and 63 patients (45%) met these criteria for first-tier postexposure testing. No cases of active TB occurred. Among coworkers, 146 had significant exposure (ie, &gt;8 hours cumulative). In the 22-month follow-up period after the exposure, no purified protein derivative or interferon gamma release assay conversions or active cases of TB occurred among exposed HCWs or patients.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X17001659_abs5\" sec-type=\"conclusions\"><jats:title>CONCLUSIONS<\/jats:title><jats:p>Electronic medical records and employee scheduling systems are useful resources to conduct otherwise labor-intensive contact investigations. Despite the high-risk features of our index case, a highly vulnerable immunocompromised patient population, and extended proximity to coworkers, we did not find any evidence of transmission of active or latent tuberculosis infection among exposed individuals.<\/jats:p><jats:p><jats:italic>Infect Control Hosp Epidemiol<\/jats:italic>2017;38:1235\u20131239<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2017.165","type":"journal-article","created":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T02:07:36Z","timestamp":1502330856000},"page":"1235-1239","source":"Crossref","is-referenced-by-count":5,"title":["Utilization of Electronic Health Record Events to Conduct a Tuberculosis Contact Investigation in a High-Risk Oncology Unit"],"prefix":"10.1017","volume":"38","author":[{"given":"Shauna C.","family":"Usiak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian A.","family":"Romero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrice","family":"Schwegman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Violet","family":"Fitzpatrick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MaryAnn","family":"Connor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet","family":"Eagan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur E.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mini","family":"Kamboj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2017,8,10]]},"reference":[{"key":"S0899823X17001659_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00499-5"},{"key":"S0899823X17001659_ref18","doi-asserted-by":"crossref","unstructured":"Arguello-Perez E EC , Schneider WJ , Del Castillo MC , et al. Latent tuberculosis infection (LTBI) among healthcare workers (HCWs): 10 years of experience at Memorial Sloan Kettering Cancer Center (MSK). Infectious Disease Week (ID Week), San Diego, CA, October 7\u201311, 2015; poster 329.","DOI":"10.1093\/ofid\/ofv133.205"},{"key":"S0899823X17001659_ref5","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.165.7.2107040"},{"key":"S0899823X17001659_ref20","unstructured":"Tuberculosis and air travel. Guidelines for prevention and control. Third Edition. WHO. http:\/\/www.who.int\/tb\/publications\/2008\/WHO_HTM_TB_2008.399_eng.pdf. Published 2008. 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Recommendations from the National Tuberculosis Controllers Association and CDC","volume":"54","year":"2005","journal-title":"MMWR Recomm Rep"},{"key":"S0899823X17001659_ref1","first-page":"807","article-title":"Response of patients infected with isoniazid-resistant tubercle bacilli to treatment with isoniazid plus PAS or isoniazid alone","volume":"25","author":"Devadatta","year":"1961","journal-title":"Bull World Health Organ"},{"key":"S0899823X17001659_ref16","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-2575"},{"key":"S0899823X17001659_ref7","unstructured":"Bureau of Tuberculosis Control Annual Summary. 2014. New York City Department of Health and Mental Hygiene website. https:\/\/www1.nyc.gov\/assets\/doh\/downloads\/pdf\/tb\/tb2014.pdf. Published 2015. 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