{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T21:20:37Z","timestamp":1773436837518,"version":"3.50.1"},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2018,6,28]],"date-time":"2018-06-28T00:00:00Z","timestamp":1530144000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2018,9]]},"abstract":"Objective<\/jats:title>To describe the 5-year findings after a policy to screen for, diagnose, and isolate medical center employees with adenoviral conjunctivitis was implemented.<\/jats:p><\/jats:sec>Design<\/jats:title>Observational report with a retrospective evaluation of a current quality improvement initiative.<\/jats:p><\/jats:sec>Setting<\/jats:title>Johns Hopkins Medicine, Baltimore, Maryland.<\/jats:p><\/jats:sec>Participants<\/jats:title>Johns Hopkins Medicine employees.<\/jats:p><\/jats:sec>Methods<\/jats:title>Data were retrieved from records maintained for this initiative, in which employees with suspected adenoviral conjunctivitis were evaluated in the Occupational Health Clinic and swabbed for polymerase chain reaction (PCR) testing for adenoviral conjunctivitis. Signs, symptoms, work area, diagnoses, and disposition of employees with eye complaints as well as PCR result and adenoviral type were recorded. Five-year data were reviewed.<\/jats:p><\/jats:sec>Results<\/jats:title>From 2011 to 2016, of 10,000 full-time equivalent employees, 1,059 employees visited the Occupational Health Clinic with suspicion of adenoviral conjunctivitis. Of these, 104 (10%) were PCR positive for adenovirus. Of these PCR-positive employees, 26 (25%) had the worst clinical presentation, epidemic keratoconjunctivitis (EKC). The Outpatient Pharmacy had the highest number of adenoviral conjunctivitis cases (n=9). The proportion of red-eye employees having PCR-positive adenoviral conjunctivitis increased over 5 years (P<\/jats:italic><.005, Cochrane-Armitage test for trend) as did the proportion of employees with EKC (P<\/jats:italic><.05). The proportion of employees with EKC caused by type 37 also increased (P<\/jats:italic><.05).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Adenoviral conjunctivitis represents 10% of employee cases clinically suspected of this infection. Employees in patient-care areas should be screened even if they have no direct patient contact. Despite increases in the proportions of adenoviral conjunctivitis and of EKC over 5 years, no outbreaks occurred. This policy helps identify incipient EKC outbreaks and guides infection control efforts.<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2018.145","type":"journal-article","created":{"date-parts":[[2018,6,28]],"date-time":"2018-06-28T06:33:34Z","timestamp":1530167614000},"page":"1080-1085","source":"Crossref","is-referenced-by-count":14,"title":["Five-year trends in adenoviral conjunctivitis in employees of one medical center"],"prefix":"10.1017","volume":"39","author":[{"given":"Irene C.","family":"Kuo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colleen","family":"Espinosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2018,6,28]]},"reference":[{"key":"S0899823X18001459_ref4","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/160.6.938"},{"key":"S0899823X18001459_ref10","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/j.ophtha.2010.12.004","article-title":"A 13-year retrospective review of polymerase chain reaction testing for infectiousagents from ocular samples","volume":"118","author":"Thompson","year":"2011","journal-title":"Ophthalmology"},{"key":"S0899823X18001459_ref17","unstructured":"Killerby ME , Stuckey M , Guendel I , Sakthivel S , et al. Notes from the field: epidemic keratoconjunctivitis outbreak associated with human adenovirus type 8\u2014US Virgin Islands, June\u2013November 2016. MMWR 2017;66:811\u2013812. Centers for Disease Control and Prevention website. https:\/\/www.cdc.gov\/mmwr\/volumes\/66\/wr\/mm6630a3.htm. Published 2017. Accessed December 4, 2017."},{"key":"S0899823X18001459_ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-005-0722-7"},{"key":"S0899823X18001459_ref2","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.66.436"},{"key":"S0899823X18001459_ref15","first-page":"8","article-title":"Molecular epidemiology of adenovirus conjunctivitis in Glasgow 1981\u20131991","volume":"7","author":"O\u2019Donnell","year":"1993","journal-title":"Eye (Lond)"},{"key":"S0899823X18001459_ref11","doi-asserted-by":"publisher","DOI":"10.1185\/03007990903038269"},{"key":"S0899823X18001459_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2007.12.012"},{"key":"S0899823X18001459_ref14","doi-asserted-by":"publisher","DOI":"10.1086\/522188"},{"key":"S0899823X18001459_ref7","doi-asserted-by":"publisher","DOI":"10.1067\/mic.2002.125193"},{"key":"S0899823X18001459_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2015.12.007"},{"key":"S0899823X18001459_ref8","doi-asserted-by":"publisher","DOI":"10.1086\/676428"},{"key":"S0899823X18001459_ref18","unstructured":"Massey J , Henry R , Minnich L , Lamson D St , George K . Notes from the field: healthcare-associated outbreak of epidemic keratoconjunctivitis\u2014West Virginia, 2015. MMWR 2016;65;382\u2013383. Centers for Disease Control and Prevention website. https:\/\/www.cdc.gov\/mmwr\/volumes\/65\/wr\/mm6514a5.htm. Published 2016. Accessed December 4, 2017."},{"key":"S0899823X18001459_ref3","first-page":"826","article-title":"Simultaneous nosocomial and community outbreak of epidemic keratoconjunctivitis with types 8 and 19 adenovirus","volume":"81","author":"Vastine","year":"1976","journal-title":"Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol"},{"key":"S0899823X18001459_ref6","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0196-6553(98)70035-5","article-title":"Epidemic keratoconjunctivitis outbreak at a tertiary referral eye care clinic","volume":"26","author":"Scharf","year":"1998","journal-title":"Am J Infect Control"},{"key":"S0899823X18001459_ref5","unstructured":"Adenovirus-associated epidemic keratoconjunctivitis outbreaks\u2014four states, 2008\u20132010. MMWR 2013;62:637\u2013641. Centers for Disease Control and Prevention website. http:\/\/www.cdc.gov\/mmwr\/preview\/mmwrhtml\/mm6232a1.htm. Published 2013. Accessed August 27, 2017."},{"key":"S0899823X18001459_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2012.04.009"},{"key":"S0899823X18001459_ref12","doi-asserted-by":"publisher","DOI":"10.1186\/1743-422X-10-193"}],"container-title":["Infection Control & Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0899823X18001459","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T11:29:55Z","timestamp":1693740595000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0899823X18001459\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,28]]},"references-count":18,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S0899823X18001459"],"URL":"https:\/\/doi.org\/10.1017\/ice.2018.145","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,28]]}}}