{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T09:33:32Z","timestamp":1787564012441,"version":"build-2736575974"},"reference-count":28,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2018,11,9]],"date-time":"2018-11-09T00:00:00Z","timestamp":1541721600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0899823X1800288X_abs1\" sec-type=\"general\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To quantify the frequency and outcomes of receiving an antibiotic prescription upon discharge from the hospital to long-term care facilities (LTCFs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X1800288X_abs2\" sec-type=\"general\">\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X1800288X_abs3\" sec-type=\"general\">\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>A 576-bed, academic hospital in Portland, Oregon.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X1800288X_abs4\" sec-type=\"general\">\n                    <jats:title>Patients<\/jats:title>\n                    <jats:p>Adult inpatients (\u226518 years of age) discharged to an LTCF between January 1, 2012, and June 30, 2016.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X1800288X_abs5\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Our primary outcome was receiving a systemic antibiotic prescription upon discharge to an LTCF. We also quantified the association between receiving an antibiotic prescription and 30-day hospital readmission, 30-day emergency department (ED) visit, and\n                      <jats:italic>Clostridium difficile<\/jats:italic>\n                      infection (CDI) on a readmission or ED visit at the index facility within 60 days of discharge.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X1800288X_abs6\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 6,701 discharges to an LTCF, 22.9% were prescribed antibiotics upon discharge. The most prevalent antibiotic classes prescribed were cephalosporins (20.4%), fluoroquinolones (19.1%), and penicillins (16.7%). The medical records of ~82% of patients included a diagnosis code for a bacterial infection on the index admission. Among patients prescribed an antibiotic upon discharge, the incidence of 30-day hospital readmission to the index facility was 15.9%, the incidence of 30-day ED visit at the index facility was 11.0%, and the incidence of CDI on a readmission or ED visit within 60 days of discharge was 1.6%. Receiving an antibiotic prescription upon discharge was significantly associated with 30-day ED visits (adjusted odds ratio [aOR], 1.2; 95% confidence interval [CI], 1.02\u20131.5) and with CDI within 60 days (aOR, 1.7; 95% CI, 1.02\u20132.8) but not with 30-day readmissions (aOR, 1.01; 95% CI, 0.9\u20131.2).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X1800288X_abs7\" sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Antibiotics were frequently prescribed upon discharge to LTCFs, which may be associated with increased risk of poor outcomes post discharge.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/ice.2018.288","type":"journal-article","created":{"date-parts":[[2018,11,9]],"date-time":"2018-11-09T04:42:25Z","timestamp":1541738545000},"page":"18-23","source":"Crossref","is-referenced-by-count":20,"title":["Antibiotic prescribing upon discharge from the hospital to long-term care facilities: Implications for antimicrobial stewardship requirements in post-acute settings"],"prefix":"10.1017","volume":"40","author":[{"given":"Bo R.","family":"Weber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brie N.","family":"Noble","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David T.","family":"Bearden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Crnich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine D.","family":"Ellingson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessina C.","family":"McGregor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon P.","family":"Furuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2018,11,9]]},"reference":[{"key":"S0899823X1800288X_ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2006.00768.x"},{"key":"S0899823X1800288X_ref27","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.14907"},{"key":"S0899823X1800288X_ref24","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2016.276"},{"key":"S0899823X1800288X_ref19","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.14557"},{"key":"S0899823X1800288X_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2015.11.005"},{"key":"S0899823X1800288X_ref2","doi-asserted-by":"publisher","DOI":"10.1086\/501798"},{"key":"S0899823X1800288X_ref6","doi-asserted-by":"publisher","DOI":"10.1086\/668031"},{"key":"S0899823X1800288X_ref11","unstructured":"US Department of Health and Human Services. Core elements of hospital antibiotic stewardship programs. Centers for Disease Control and Prevention website. https:\/\/www.cdc.gov\/antibiotic-use\/healthcare\/implementation\/core-elements.html. Published 2014."},{"key":"S0899823X1800288X_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2015.11.013"},{"key":"S0899823X1800288X_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2004.12.021"},{"key":"S0899823X1800288X_ref7","doi-asserted-by":"publisher","DOI":"10.1086\/665711"},{"key":"S0899823X1800288X_ref4","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2013.3029"},{"key":"S0899823X1800288X_ref26","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2009.0629"},{"key":"S0899823X1800288X_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2012.04.004"},{"key":"S0899823X1800288X_ref9","unstructured":"Medicare and Medicaid Programs; Reform of requirements for long-term care facilities. Federal Register website. https:\/\/www.federalregister.gov\/documents\/2016\/10\/04\/2016-23503\/medicare-and-medicaid-programs-reform-of-requirements-for-long-term-care-facilities. Published 2016. Accessed May 22, 2018."},{"key":"S0899823X1800288X_ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2010.02768.x"},{"key":"S0899823X1800288X_ref13","first-page":"21","article-title":"Entangled practices, entangled epidemics: antibiotic practices and healthcare associated infections in nursing homes and hospitals","volume":"2","author":"Lapane","year":"2016","journal-title":"J Nursing Home Res"},{"key":"S0899823X1800288X_ref14","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.14766"},{"key":"S0899823X1800288X_ref15","first-page":"CD003543","article-title":"Interventions to improve antibiotic prescribing practices for hospital inpatients","volume":"2","author":"Davey","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"S0899823X1800288X_ref16","doi-asserted-by":"publisher","DOI":"10.1097\/NCM.0000000000000199"},{"key":"S0899823X1800288X_ref17","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-006442"},{"key":"S0899823X1800288X_ref18","doi-asserted-by":"publisher","DOI":"10.1080\/20009666.2017.1313492"},{"key":"S0899823X1800288X_ref20","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02873-14"},{"key":"S0899823X1800288X_ref21","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2016.0487"},{"key":"S0899823X1800288X_ref22","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.15246"},{"key":"S0899823X1800288X_ref25","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-158-5-201303051-00006"},{"key":"S0899823X1800288X_ref3","doi-asserted-by":"publisher","DOI":"10.7326\/M15-1754"},{"key":"S0899823X1800288X_ref28","doi-asserted-by":"publisher","DOI":"10.1086\/665725"}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0899823X1800288X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T17:15:27Z","timestamp":1555089327000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0899823X1800288X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,9]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["S0899823X1800288X"],"URL":"https:\/\/doi.org\/10.1017\/ice.2018.288","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,9]]}}}