{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T16:35:51Z","timestamp":1770741351428,"version":"3.49.0"},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T00:00:00Z","timestamp":1558051200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0899823X19001235_as1\"><jats:title>Objective:<\/jats:title><jats:p>Healthcare-associated infections (HAIs) are a significant burden on healthcare facilities. Universal gloving is a horizontal intervention to prevent transmission of pathogens that cause HAI. In this meta-analysis, we aimed to identify whether implementation of universal gloving is associated with decreased incidence of HAI in clinical settings.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X19001235_as2\"><jats:title>Methods:<\/jats:title><jats:p>A systematic literature search was conducted to find all relevant publications using search terms for universal gloving and HAIs. Pooled incidence rate ratios (IRRs) and 95% confidence intervals (CIs) were calculated using random effects models. Heterogeneity was evaluated using the Woolf test and the I<jats:sup>2<\/jats:sup> test.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X19001235_as3\"><jats:title>Results:<\/jats:title><jats:p>In total, 8 studies were included. These studies were moderately to substantially heterogeneous (I<jats:sup>2<\/jats:sup> = 59%) and had varied results. Stratified analyses showed a nonsignificant association between universal gloving and incidence of methicillin-resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (MRSA; pooled IRR, 0.94; 95% CI, 0.79\u20131.11) and vancomycin-resistant enterococci (VRE; pooled IRR, 0.94; 95% CI, 0.69\u20131.28). Studies that implemented universal gloving alone showed a significant association with decreased incidence of HAI (IRR, 0.77; 95% CI, 0.67\u20130.89), but studies implementing universal gloving as part of intervention bundles showed no significant association with incidence of HAI (IRR, 0.95; 95% CI, 0.86\u20131.05).<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X19001235_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>Universal gloving may be associated with a small protective effect against HAI. Despite limited data, universal gloving may be considered in high-risk settings, such as pediatric intensive care units. Further research should be performed to determine the effects of universal gloving on a broader range of pathogens, including gram-negative pathogens.<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2019.123","type":"journal-article","created":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T06:09:19Z","timestamp":1558073359000},"page":"755-760","source":"Crossref","is-referenced-by-count":15,"title":["Association between universal gloving and healthcare-associated infections: A systematic literature review and meta-analysis"],"prefix":"10.1017","volume":"40","author":[{"given":"Nai-Chung N.","family":"Chang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley E.","family":"Kates","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa A.","family":"Ward","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth J.","family":"Kiscaden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather Schacht","family":"Reisinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eli N.","family":"Perencevich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3604-0093","authenticated-orcid":false,"given":"Marin L.","family":"Schweizer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the CDC Prevention Epicenters Program","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2019,5,17]]},"reference":[{"key":"S0899823X19001235_ref19","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198906293202603"},{"key":"S0899823X19001235_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2007.02.011"},{"key":"S0899823X19001235_ref11","doi-asserted-by":"publisher","DOI":"10.1136\/jech.52.6.377"},{"key":"S0899823X19001235_ref9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7398.1083"},{"key":"S0899823X19001235_ref8","doi-asserted-by":"publisher","DOI":"10.1177\/1757177414562057"},{"key":"S0899823X19001235_ref7","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis016"},{"key":"S0899823X19001235_ref4","doi-asserted-by":"publisher","DOI":"10.1086\/338234"},{"key":"S0899823X19001235_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2010.05.002"},{"key":"S0899823X19001235_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2007.10.007"},{"key":"S0899823X19001235_ref1","unstructured":"1. Center for Disease Control and Prevention. Isolation Precautions Guidelines Library | Infection Control | CDC. https:\/\/www.cdc.gov\/infectioncontrol\/guidelines\/isolation\/index.html. 2017. 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