{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T07:14:06Z","timestamp":1792394046921,"version":"4.4.0"},"reference-count":31,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T00:00:00Z","timestamp":1574726400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0899823X19002964_as1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Describe common pathogens and antimicrobial resistance patterns for healthcare-associated infections (HAIs) that occurred during 2015\u20132017 and were reported to the Centers for Disease Control and Prevention\u2019s (CDC\u2019s) National Healthcare Safety Network (NHSN).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X19002964_as2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Data from central line-associated bloodstream infections (CLABSIs), catheter-associated urinary tract infections (CAUTIs), ventilator-associated events (VAEs), and surgical site infections (SSIs) were reported from acute-care hospitals, long-term acute-care hospitals, and inpatient rehabilitation facilities. This analysis included device-associated HAIs reported from adult location types, and SSIs among patients \u226518 years old. Percentages of pathogens with nonsusceptibility (%NS) to selected antimicrobials were calculated for each HAI type, location type, surgical category, and surgical wound closure technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X19002964_as3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Overall, 5,626 facilities performed adult HAI surveillance during this period, most of which were general acute-care hospitals with &lt;200 beds.\n                      <jats:italic>Escherichia coli<\/jats:italic>\n                      (18%),\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      (12%), and\n                      <jats:italic>Klebsiella<\/jats:italic>\n                      spp (9%) were the 3 most frequently reported pathogens. Pathogens varied by HAI and location type, with oncology units having a distinct pathogen distribution compared to other settings. The %NS for most pathogens was significantly higher among device-associated HAIs than SSIs. In addition, pathogens from long-term acute-care hospitals had a significantly higher %NS than those from general hospital wards.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X19002964_as4\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This report provides an updated national summary of pathogen distributions and antimicrobial resistance among select HAIs and pathogens, stratified by several factors. These data underscore the importance of tracking antimicrobial resistance, particularly in vulnerable populations such as long-term acute-care hospitals and intensive care units.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/ice.2019.296","type":"journal-article","created":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T02:53:51Z","timestamp":1574736831000},"page":"1-18","source":"Crossref","is-referenced-by-count":542,"title":["Antimicrobial-resistant pathogens associated with adult healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015\u20132017"],"prefix":"10.1017","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7327-9108","authenticated-orcid":false,"given":"Lindsey M.","family":"Weiner-Lastinger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila","family":"Abner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan R.","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander J.","family":"Kallen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Karlsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelley S.","family":"Magill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Pollock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac","family":"See","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minn M.","family":"Soe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maroya S.","family":"Walters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret A.","family":"Dudeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2019,11,26]]},"reference":[{"key":"S0899823X19002964_ref22","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6713e1"},{"key":"S0899823X19002964_ref5","unstructured":"5. Long-term Care Hospital (LTCH) Quality Reporting Program (QRP). Centers for Medicare and Medicaid Services website. https:\/\/www.cms.gov\/Medicare\/Quality-Initiatives-Patient-Assessment-Instruments\/LTCH-Quality-Reporting\/index.html. Updated 2019. Accessed June 3, 2019."},{"key":"S0899823X19002964_ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2003.12.019"},{"key":"S0899823X19002964_ref8","unstructured":"8. Urinary tract infection (catheter-associated urinary tract infection [CAUTI] and non-catheter-associated urinary tract infection [UTI]) and other urinary system infection [USI]) events. Centers for Disease Control and Prevention (CDC) website. http:\/\/www.cdc.gov\/nhsn\/PDFs\/pscManual\/7pscCAUTIcurrent.pdf. Updated January 2019. Accessed June 3, 2019."},{"key":"S0899823X19002964_ref20","first-page":"1","article-title":"The SHIELD Orange County Project\u2014multi drug-resistant organism (MDRO) prevalence in 21 nursing homes and long-term acute-care facilities in southern California","volume":"119","author":"McKinnell","year":"2019","journal-title":"Clin Infect Dis"},{"key":"S0899823X19002964_ref3","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2016.174"},{"key":"S0899823X19002964_ref23","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6509e1"},{"key":"S0899823X19002964_ref9","unstructured":"9. Ventilator-associated event (VAE). Centers for Disease Control and Prevention (CDC) website. https:\/\/www.cdc.gov\/nhsn\/pdfs\/pscmanual\/10-vae_final.pdf. Updated January 2019. Accessed June 3, 2019."},{"key":"S0899823X19002964_ref15","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing","year":"2017"},{"key":"S0899823X19002964_ref28","doi-asserted-by":"publisher","DOI":"10.1086\/321893"},{"key":"S0899823X19002964_ref1","doi-asserted-by":"publisher","DOI":"10.1086\/591861"},{"key":"S0899823X19002964_ref6","unstructured":"6. Inpatient Rehabilitation Facilities (IRF) Quality Reporting Program (QRP). Centers for Medicare and Medicaid Services website. https:\/\/www.cms.gov\/Medicare\/Quality-Initiatives-Patient-Assessment-Instruments\/IRF-Quality-Reporting\/index.html. Updated 2018. Accessed June 3, 2019."},{"key":"S0899823X19002964_ref10","unstructured":"10. Surgical site infection (SSI) event. Centers for Disease Control and Prevention (CDC) website. http:\/\/www.cdc.gov\/nhsn\/PDFs\/pscManual\/9pscSSIcurrent.pdf. Updated January 2019. Accessed June 3, 2019."},{"key":"S0899823X19002964_ref11","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofu052.561"},{"key":"S0899823X19002964_ref4","unstructured":"4. Acute Inpatient PPS. Centers for Medicare and Medicaid Services website. https:\/\/www.cms.gov\/Medicare\/Medicare-Fee-for-Service-Payment\/AcuteInpatientPPS\/index.html. Updated 2019. Accessed June 3, 2019."},{"key":"S0899823X19002964_ref7","unstructured":"7. Bloodstream infection event (central line-associated bloodstream infection and non-central line-associated bloodstream infection). Centers for Disease Control and Prevention (CDC) website. http:\/\/www.cdc.gov\/nhsn\/PDFs\/pscManual\/4PSC_CLABScurrent.pdf. Updated January 2019. Accessed June 3, 2019."},{"key":"S0899823X19002964_ref12","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2017.236"},{"key":"S0899823X19002964_ref13","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2019.297"},{"key":"S0899823X19002964_ref14","unstructured":"14. The 2015\u20132017 adult antimicrobial resistance\u00a0report online supplement. Centers for Disease Control and Prevention (CDC) website. https:\/\/www.cdc.gov\/nhsn\/datastat\/index.html. Updated September 2019. Accessed October 14, 2019."},{"key":"S0899823X19002964_ref16","unstructured":"16. Systematized Nomenclature of Medicine\u2013Clinical Terms (SNOMED CT) Browser: United States edition. SNOMED International website. https:\/\/browser.ihtsdotools.org Updated 2019. Accessed June 4, 2019."},{"key":"S0899823X19002964_ref17","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.001572"},{"key":"S0899823X19002964_ref18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x"},{"key":"S0899823X19002964_ref19","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw113"},{"key":"S0899823X19002964_ref21","doi-asserted-by":"publisher","DOI":"10.1086\/649226"},{"key":"S0899823X19002964_ref24","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6430a4"},{"key":"S0899823X19002964_ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2005.11.044"},{"key":"S0899823X19002964_ref27","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/24.2.211"},{"key":"S0899823X19002964_ref30","unstructured":"30. The 2017 national and state HAI progress report. Centers for Disease Control and Prevention (CDC) website. https:\/\/www.cdc.gov\/hai\/data\/portal\/progress-report.html. Published March 2019. Accessed July 3, 2019."},{"key":"S0899823X19002964_ref31","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ1194"},{"key":"S0899823X19002964_ref2","doi-asserted-by":"publisher","DOI":"10.1086\/668770"},{"key":"S0899823X19002964_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-6701(08)60017-1"}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0899823X19002964","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T09:34:35Z","timestamp":1576661675000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0899823X19002964\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,26]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["S0899823X19002964"],"URL":"https:\/\/doi.org\/10.1017\/ice.2019.296","relation":{"is-referenced-by":[{"id-type":"doi","id":"10.1186\/s12866-026-05250-x","asserted-by":"object"}]},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,26]]}}}