{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T07:20:15Z","timestamp":1775114415750,"version":"3.50.1"},"reference-count":9,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2020,11,26]],"date-time":"2020-11-26T00:00:00Z","timestamp":1606348800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0899823X20012672_as1\"><jats:title>Objective:<\/jats:title><jats:p>To develop a pediatric research agenda focused on pediatric healthcare-associated infections and antimicrobial stewardship topics that will yield the highest impact on child health.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X20012672_as2\"><jats:title>Participants:<\/jats:title><jats:p>The study included 26 geographically diverse adult and pediatric infectious diseases clinicians with expertise in healthcare-associated infection prevention and\/or antimicrobial stewardship (topic identification and ranking of priorities), as well as members of the Division of Healthcare Quality and Promotion at the Centers for Disease Control and Prevention (topic identification).<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X20012672_as3\"><jats:title>Methods:<\/jats:title><jats:p>Using a modified Delphi approach, expert recommendations were generated through an iterative process for identifying pediatric research priorities in healthcare associated infection prevention and antimicrobial stewardship. The multistep, 7-month process included a literature review, interactive teleconferences, web-based surveys, and 2 in-person meetings.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X20012672_as4\"><jats:title>Results:<\/jats:title><jats:p>A final list of 12 high-priority research topics were generated in the 2 domains. High-priority healthcare-associated infection topics included judicious testing for <jats:italic>Clostridioides difficile<\/jats:italic> infection, chlorhexidine (CHG) bathing, measuring and preventing hospital-onset bloodstream infection rates, surgical site infection prevention, surveillance and prevention of multidrug resistant gram-negative rod infections. Antimicrobial stewardship topics included \u03b2-lactam allergy de-labeling, judicious use of perioperative antibiotics, intravenous to oral conversion of antimicrobial therapy, developing a patient-level \u201charm index\u201d for antibiotic exposure, and benchmarking and or peer comparison of antibiotic use for common inpatient conditions.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X20012672_as5\"><jats:title>Conclusions:<\/jats:title><jats:p>We identified 6 healthcare-associated infection topics and 6 antimicrobial stewardship topics as potentially high-impact targets for pediatric research.<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2020.1267","type":"journal-article","created":{"date-parts":[[2020,11,26]],"date-time":"2020-11-26T07:57:34Z","timestamp":1606377454000},"page":"519-522","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":15,"title":["Pediatric research priorities in healthcare-associated infections and antimicrobial stewardship"],"prefix":"10.1017","volume":"42","author":[{"given":"Susan E.","family":"Coffin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisca","family":"Abanyie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina","family":"Bryant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Cantey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Fiore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Fritz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Guzman-Cottrill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam L.","family":"Hersh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. 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