{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T20:15:25Z","timestamp":1775247325816,"version":"3.50.1"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T00:00:00Z","timestamp":1596412800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0899823X20003992_as1\">\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Prolonged survival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on environmental surfaces and personal protective equipment may lead to these surfaces transmitting this pathogen to others. We sought to determine the effectiveness of a pulsed-xenon ultraviolet (PX-UV) disinfection system in reducing the load of SARS-CoV-2 on hard surfaces and N95 respirators.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X20003992_as2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Chamber slides and N95 respirator material were directly inoculated with SARS-CoV-2 and were exposed to different durations of PX-UV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X20003992_as3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      For hard surfaces, disinfection for 1, 2, and 5 minutes resulted in 3.53 log\n                      <jats:sub>10<\/jats:sub>\n                      , &gt;4.54 log\n                      <jats:sub>10<\/jats:sub>\n                      , and &gt;4.12 log\n                      <jats:sub>10<\/jats:sub>\n                      reductions in viral load, respectively. For N95 respirators, disinfection for 5 minutes resulted in &gt;4.79 log\n                      <jats:sub>10<\/jats:sub>\n                      reduction in viral load. PX-UV significantly reduced SARS-CoV-2 on hard surfaces and N95 respirators.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X20003992_as4\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>With the potential to rapidly disinfectant environmental surfaces and N95 respirators, PX-UV devices are a promising technology to reduce environmental and personal protective equipment bioburden and to enhance both healthcare worker and patient safety by reducing the risk of exposure to SARS-CoV-2.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/ice.2020.399","type":"journal-article","created":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T03:52:25Z","timestamp":1596426745000},"page":"127-130","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":60,"title":["Deactivation of SARS-CoV-2 with pulsed-xenon ultraviolet light: Implications for environmental COVID-19 control"],"prefix":"10.1017","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2653-2243","authenticated-orcid":false,"given":"Sarah E.","family":"Simmons","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Ricardo","family":"Carrion","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kendra J.","family":"Alfson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilary M.","family":"Staples","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chetan","family":"Jinadatha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William R.","family":"Jarvis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priya","family":"Sampathkumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roy F.","family":"Chemaly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fareed","family":"Khawaja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Povroznik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith S.","family":"Kaye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert M.","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark A.","family":"Stibich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2020,8,3]]},"reference":[{"key":"S0899823X20003992_ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2006100"},{"key":"S0899823X20003992_ref13","doi-asserted-by":"publisher","DOI":"10.3201\/eid2606.200412"},{"key":"S0899823X20003992_ref16","unstructured":"16. 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Accessed April 16, 2020."},{"key":"S0899823X20003992_ref28","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-01999-9","volume-title":"Ultraviolet Germicidal Irradiation Handbook: UVGI for Air and Surface Disinfection.","author":"Kowalski","year":"2009"},{"key":"S0899823X20003992_ref25","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1186\/s12879-017-2895-6","article-title":"Interaction of healthcare worker hands and portable medical equipment: a sequence analysis to show potential transmission opportunities","volume":"17","author":"Jinadatha","year":"2017","journal-title":"BMC Infect Dis"},{"key":"S0899823X20003992_ref15","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1086\/591940","article-title":"Improving cleaning of the environment surrounding patients in 36 acute care hospitals","volume":"29","author":"Carling","year":"2008","journal-title":"Infect Control Hosp Epidemiol"},{"key":"S0899823X20003992_ref3","doi-asserted-by":"publisher","DOI":"10.3201\/eid2607.200885"},{"key":"S0899823X20003992_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2013.12.013"},{"key":"S0899823X20003992_ref14","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6912e3"}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0899823X20003992","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T04:29:23Z","timestamp":1613622563000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0899823X20003992\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,3]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["S0899823X20003992"],"URL":"https:\/\/doi.org\/10.1017\/ice.2020.399","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.05.06.20093658","asserted-by":"object"}]},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,3]]},"assertion":[{"value":"\u00a9 2020 by The Society for Healthcare Epidemiology of America. All rights reserved.","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}