{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T15:54:07Z","timestamp":1764431647540,"version":"3.40.5"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T00:00:00Z","timestamp":1584576000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0899823X20000537_as1\" sec-type=\"other\"><jats:title>Objective:<\/jats:title><jats:p>To determine the prevalence of antibiotic allergy labels (AALs) in Australian aged care residents and to describe the impact of labels on antibiotic prescribing practices.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X20000537_as2\" sec-type=\"other\"><jats:title>Design:<\/jats:title><jats:p>Point-prevalence survey.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X20000537_as3\" sec-type=\"other\"><jats:title>Setting:<\/jats:title><jats:p>Australian residential aged care facilities.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X20000537_as4\" sec-type=\"other\"><jats:title>Participants:<\/jats:title><jats:p>We surveyed 1,489 residents in 407 aged care facilities.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X20000537_as5\" sec-type=\"other\"><jats:title>Methods:<\/jats:title><jats:p>Standardized data were collected on a single day between June 1 and August 31, 2018, for residents prescribed an antibiotic. An AAL was reported if it was documented in the resident\u2019s health record. Resident-level data were used to calculate overall prevalence, and antibiotic-level data were used to report relative frequency of AALs for individual antibiotics and classes.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X20000537_as6\" sec-type=\"other\"><jats:title>Results:<\/jats:title><jats:p>Among 1,489 residents, 356 (24%) had 1 or more documented AALs. The AALs for penicillin (28.3%), amoxicillin or amoxicillin\/clavulanic acid (10.5%), cefalexin (7.2%), and trimethoprim (7.0%) were most commonly reported. The presence of an AAL was associated with significantly less prescribing of penicillins (OR, 0.43; 95% CI, 0.31\u20130.62; <jats:italic>P<\/jats:italic> &lt; .001) and significantly more prescribing of lincosamides (OR, 4.81; <jats:italic>P<\/jats:italic> &lt; .001), macrolides (OR, 2.03; <jats:italic>P<\/jats:italic> = .007), and tetracyclines (OR, 1.54; <jats:italic>P<\/jats:italic> = .033). Of residents with AALs, 7 residents (1.9%) were prescribed an antibiotic that was listed on the allergy section of their health record.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X20000537_as7\" sec-type=\"other\"><jats:title>Conclusions:<\/jats:title><jats:p>A high prevalence of AALs was observed among residents of Australian aged care facilities, comparable to the prevalence of AALs in high-risk hospitalized patients. Significant increases in prescribing of lincosamide, macrolide, and tetracycline agents poses a potential risk to aged populations, and future studies must evaluate the benefits of AAL delabelling programs tailored for aged care settings.<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2020.53","type":"journal-article","created":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T07:17:27Z","timestamp":1584602247000},"page":"641-644","source":"Crossref","is-referenced-by-count":5,"title":["Burden of antibiotic allergy labels in Australian aged care residents: Findings from a national point-prevalence survey"],"prefix":"10.1017","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1321-7271","authenticated-orcid":false,"given":"Laura","family":"Travis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leon J.","family":"Worth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Trubiano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Thursky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noleen","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2020,3,19]]},"reference":[{"key":"S0899823X20000537_ref23","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky575"},{"key":"S0899823X20000537_ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-015-0063-6"},{"key":"S0899823X20000537_ref22","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k2400"},{"key":"S0899823X20000537_ref13","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.18.2819"},{"key":"S0899823X20000537_ref24","doi-asserted-by":"publisher","DOI":"10.1111\/1742-6723.12774"},{"key":"S0899823X20000537_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2013.01.006"},{"key":"S0899823X20000537_ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-015-1303-3"},{"key":"S0899823X20000537_ref14","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.13830"},{"key":"S0899823X20000537_ref4","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00078-17"},{"key":"S0899823X20000537_ref15","doi-asserted-by":"publisher","DOI":"10.4212\/cjhp.v71i1.1726"},{"key":"S0899823X20000537_ref5","doi-asserted-by":"publisher","DOI":"10.1111\/imj.13223"},{"key":"S0899823X20000537_ref2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix244"},{"volume-title":"2017\u201318 Report on the Operation of the Aged Care Act 1997","year":"2018","key":"S0899823X20000537_ref20"},{"key":"S0899823X20000537_ref10","doi-asserted-by":"publisher","DOI":"10.1592\/phco.31.8.742"},{"key":"S0899823X20000537_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2016.03.009"},{"key":"S0899823X20000537_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32218-9"},{"key":"S0899823X20000537_ref3","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy037"},{"key":"S0899823X20000537_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2009.01.034"},{"key":"S0899823X20000537_ref7","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.13058"},{"key":"S0899823X20000537_ref8","doi-asserted-by":"publisher","DOI":"10.5694\/mja15.01329"},{"key":"S0899823X20000537_ref9","first-page":"265","article-title":"The burden of antibiotic allergies in adults in an Australian intensive care unit: the BASIS study","volume":"21","author":"Moran","year":"2019","journal-title":"Crit Care Resusc"},{"key":"S0899823X20000537_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.09.021"},{"key":"S0899823X20000537_ref18","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.2003.01638.x"},{"volume-title":"Antimicrobial prescribing and infections in Australian residential aged care facilities: results of the 2018 Aged Care National Antimicrobial Prescribing Survey","year":"2019","key":"S0899823X20000537_ref21"},{"key":"S0899823X20000537_ref25","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2019.50"},{"key":"S0899823X20000537_ref26","doi-asserted-by":"publisher","DOI":"10.1111\/imj.13221"}],"container-title":["Infection Control &amp; 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