{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T21:00:17Z","timestamp":1776286817184,"version":"3.50.1"},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T00:00:00Z","timestamp":1621468800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0899823X21002063_as1\"><jats:title>Background:<\/jats:title><jats:p>Ultraviolet-C (UV-C) light devices could be useful to reduce environmental contamination with <jats:italic>Candida auris<\/jats:italic>. However, variable susceptibility of <jats:italic>C. auris<\/jats:italic> strains to UV-C has been reported, and the high cost of many devices limits their use in resource-limited settings.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X21002063_as2\"><jats:title>Objective:<\/jats:title><jats:p>To evaluate the efficacy of relatively low-cost (&lt;$15,000 purchase price) UV-C devices against <jats:italic>C. auris<\/jats:italic> strains from the 4 major phylogenetic clades.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X21002063_as3\"><jats:title>Methods:<\/jats:title><jats:p>A modification of the American Society for Testing and Materials (ASTM) standard quantitative disk carrier test method (ASTM E 2197) was used to examine and compare the effectiveness of UV-C devices against <jats:italic>C. auris<\/jats:italic>, methicillin-resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (MRSA), and bacteriophage Phi6. Reductions of 3 log<jats:sub>10<\/jats:sub> were considered effective. UV-C irradiance measurements and colorimetric indicators were used to assess UV-C output.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X21002063_as4\"><jats:title>Results:<\/jats:title><jats:p>Of 8 relatively low-cost UV-C devices, 6 met the criteria for effective decontamination of <jats:italic>C. auris<\/jats:italic> isolates from clades I and II, MRSA, and bacteriophage Phi6, including 3 room decontamination devices and 3 UV-C box devices. <jats:italic>Candida auris<\/jats:italic> isolates from clades III and IV were less susceptible to UV-C than clade I and II isolates; 1 relatively low-cost room decontamination device and 2 enclosed box devices met the criteria for effective decontamination of clade III and IV isolates. UV-C irradiance measurements and colorimetric indicator results were consistent with microorganism reductions.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X21002063_as5\"><jats:title>Conclusions:<\/jats:title><jats:p>Some relatively low-cost UV-C light technologies are effective against <jats:italic>C. auris,<\/jats:italic> including isolates from clades III and IV with reduced UV-C susceptibility. Studies are needed to evaluate the effectiveness of UV-C devices in clinical settings.<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2021.206","type":"journal-article","created":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T04:53:51Z","timestamp":1621486431000},"page":"747-751","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":20,"title":["Efficacy of relatively low-cost ultraviolet-C light devices against <i>Candida auris<\/i>"],"prefix":"10.1017","volume":"43","author":[{"given":"Basya S.","family":"Pearlmutter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammed F.","family":"Haq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer L.","family":"Cadnum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annette L.","family":"Jencson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Carlisle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Curtis J.","family":"Donskey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,5,20]]},"reference":[{"key":"S0899823X21002063_ref7","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2017.239"},{"key":"S0899823X21002063_ref10","doi-asserted-by":"publisher","DOI":"10.20411\/pai.v5i1.373"},{"key":"S0899823X21002063_ref15","volume-title":"Designation E2197. 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