{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:46:29Z","timestamp":1747172789746,"version":"3.40.5"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T00:00:00Z","timestamp":1622764800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2022,6]]},"abstract":"Abstract<\/jats:title>Background:<\/jats:title>We analyzed 2017 healthcare facility-onset (HO) vancomycin-resistant Enterococcus<\/jats:italic> (VRE) bacteremia data to identify hospital-level factors that were significant predictors of HO-VRE using the Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) multidrug-resistant organism and Clostridioides difficile<\/jats:italic> reporting module. A risk-adjusted model that can be used to calculate the number of predicted HO-VRE bacteremia events in a facility was developed, thus enabling the calculation of VRE standardized infection ratios (SIRs).<\/jats:p><\/jats:sec>Methods:<\/jats:title>Acute-care hospitals reporting at least 1 month of 2017 VRE bacteremia data were included in the analysis. Various hospital-level characteristics were assessed to develop a best-fit model and subsequently derive the 2018 national and state SIRs.<\/jats:p><\/jats:sec>Results:<\/jats:title>In 2017, 470 facilities in 35 states participated in VRE bacteremia surveillance. Inpatient VRE community-onset prevalence rate, average length of patient stay, outpatient VRE community-onset prevalence rate, and presence of an oncology unit were all significantly associated (all 95% likelihood ratio confidence limits excluded the nominal value of zero) with HO-VRE bacteremia. The 2018 national SIR was 1.01 (95% CI, 0.93\u20131.09) with 577 HO bacteremia events reported.<\/jats:p><\/jats:sec>Conclusion:<\/jats:title>The creation of an SIR enables national-, state-, and facility-level monitoring of VRE bacteremia while controlling for individual hospital-level factors. Hospitals can compare their VRE burden to a national benchmark to help them determine the effectiveness of infection prevention efforts over time.<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2021.215","type":"journal-article","created":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T09:47:22Z","timestamp":1622800042000},"page":"714-718","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Laboratory-identified vancomycin-resistant enterococci bacteremia incidence: A standardized infection ratio prediction model"],"prefix":"10.1017","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6600-902X","authenticated-orcid":false,"given":"Sukarma S. S.","family":"Tanwar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsey M.","family":"Weiner-Lastinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeneita M.","family":"Bell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Allen-Bridson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suparna","family":"Bagchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret A.","family":"Dudeck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan R.","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,6,4]]},"reference":[{"key":"S0899823X21002154_ref3","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2016.254"},{"key":"S0899823X21002154_ref12","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.ajic.2010.10.024","article-title":"Implications for vancomycin-resistance. Enterococcus colonization associated with Clostridium difficile infections","volume":"39","author":"Fujitani","year":"2011","journal-title":"Am J Infect Control"},{"key":"S0899823X21002154_ref1","unstructured":"1. Antibiotic resistance threats in the United States, 2019. Centers for Disease Control and Prevention website. https:\/\/www.cdc.gov\/drugresistance\/pdf\/threats-report\/2019-ar-threats-report-508.pdf. Published 2019. Accessed May 12, 2021."},{"key":"S0899823X21002154_ref9","unstructured":"9. Recommendations for preventing the spread of vancomycin resistance recommendations of the Hospital Infection Control Practices Advisory Committee (HICPAC). Morbid Mortal Wkly Rep 1995."},{"key":"S0899823X21002154_ref6","unstructured":"6. National Healthcare Safety Network Patient Safety Component Manual. Centers for Disease Control and Prevention website. https:\/\/www.cdc.gov\/nhsn\/datastat\/index.html. Published 2019. Accessed May 12, 2021."},{"key":"S0899823X21002154_ref14","doi-asserted-by":"publisher","DOI":"10.1086\/516247"},{"key":"S0899823X21002154_ref5","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.13.4.686"},{"key":"S0899823X21002154_ref8","unstructured":"8. The Hospital Value-Based Purchasing (VBP) program. Centers for Medicare and Medicaid Services website. https:\/\/www.cms.gov\/Medicare\/Quality-Initiatives-Patient-Assessment-Instruments\/Value-Based-Programs\/HVBP\/Hospital-Value-Based-Purchasing. Published 2020. Accessed May 12, 2021."},{"key":"S0899823X21002154_ref4","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2015.228"},{"key":"S0899823X21002154_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2005.08.015"},{"key":"S0899823X21002154_ref2","unstructured":"2. Antibiotic resistance threats in the United States, 2013. Centers for Disease Control and Prevention website. https:\/\/www.cdc.gov\/drugresistance\/threat-report-2013\/pdf\/ar-threats-2013-508.pdf. Published 2013. Accessed May 12, 2021."},{"key":"S0899823X21002154_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz871"},{"key":"S0899823X21002154_ref7","unstructured":"7. National Healthcare Safety Network standardized infection ration (SIR). A guide to SIR. Centers for Disease Control and Prevention website. https:\/\/www.cdc.gov\/nhsn\/datastat\/index.html. Published 2019. Accessed May 12, 2021."},{"key":"S0899823X21002154_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2018.05.003"},{"key":"S0899823X21002154_ref11","doi-asserted-by":"publisher","DOI":"10.1086\/427512"}],"container-title":["Infection Control & Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0899823X21002154","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T02:25:37Z","timestamp":1692325537000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0899823X21002154\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,4]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["S0899823X21002154"],"URL":"https:\/\/doi.org\/10.1017\/ice.2021.215","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"type":"print","value":"0899-823X"},{"type":"electronic","value":"1559-6834"}],"subject":[],"published":{"date-parts":[[2021,6,4]]},"assertion":[{"value":"\u00a9 The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}