{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T03:20:06Z","timestamp":1767151206270,"version":"build-2238731810"},"reference-count":10,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We reviewed the electronic health records of 1,419 inpatients with anterior nares (AN) and oropharynx (OP) MRSA PCR tests. Concordance was 96.5%. In discordant cases, AN negative\u2013OP positive results increased detection of probable MRSA pneumonia by only 0.3%. A dual testing approach has limited utility in detecting MRSA pneumonia and increases resource utilization.<\/jats:p>","DOI":"10.1017\/ice.2021.463","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T04:33:15Z","timestamp":1637555595000},"page":"1242-1244","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Utility of Dual Anterior Nares and Oropharynx MRSA Screening PCR for Patients with Suspected Pneumonia"],"prefix":"10.1017","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2032-7604","authenticated-orcid":false,"given":"Michael A.","family":"Kessler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandip","family":"Biswas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsokyi","family":"Choera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derrick J.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9299-3027","authenticated-orcid":false,"given":"Alexander J.","family":"Lepak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,11,22]]},"reference":[{"key":"S0899823X21004633_ref5","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1128\/AAC.01965-12","article-title":"A trial of discontinuation of empiric vancomycin therapy in patients with suspected methicillin-resistant Staphylococcus aureus healthcare-associated pneumonia","volume":"57","author":"Boyce","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"S0899823X21004633_ref8","doi-asserted-by":"crossref","first-page":"ofy162","DOI":"10.1093\/ofid\/ofy162","article-title":"Microbiology comment nudge improves pneumonia prescribing","volume":"5","author":"Musgrove","year":"2018","journal-title":"Open Forum Infect Dis"},{"key":"S0899823X21004633_ref1","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1128\/AAC.01805-13","article-title":"Predictive value of methicillin-resistant Staphylococcus aureus (MRSA) nasal swab PCR assay for MRSA pneumonia","volume":"58","author":"Dangerfield","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"S0899823X21004633_ref2","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1177\/1060028018823027","article-title":"Systematic review of the clinical utility of methicillin-resistant Staphylococcus aureus (MRSA) nasal screening for MRSA pneumonia","volume":"53","author":"Smith","year":"2019","journal-title":"Ann Pharmacother"},{"key":"S0899823X21004633_ref6","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1086\/669095","article-title":"Quantifying the impact of extranasal testing of body sites for methicillin-resistant Staphylococcus aureus colonization at the time of hospital or intensive care unit admission","volume":"34","author":"McKinnell","year":"2013","journal-title":"Infect Control Hosp Epidemiol"},{"key":"S0899823X21004633_ref4","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1093\/cid\/ciz974","article-title":"Determining the utility of methicillin-resistant Staphylococcus aureus nares screening in antimicrobial stewardship","volume":"71","author":"Mergenhagen","year":"2020","journal-title":"Clin Infect Dis"},{"key":"S0899823X21004633_ref10","first-page":"666","article-title":"Systematic review and meta-analysis of acute kidney injury associated with concomitant vancomycin and piperacillin\/tazobactam","volume":"64","author":"Hammond","year":"2017","journal-title":"Clin Infect Dis"},{"key":"S0899823X21004633_ref3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/cid\/ciy024","article-title":"The clinical utility of methicillin-resistant Staphylococcus aureus (MRSA) nasal screening to rule out MRSA pneumonia: a diagnostic meta-analysis with antimicrobial stewardship implications","volume":"67","author":"Parente","year":"2018","journal-title":"Clin Infect Dis"},{"key":"S0899823X21004633_ref9","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1164\/rccm.201908-1581ST","article-title":"Diagnosis and Treatment of adults with community-acquired pneumonia. An official clinical practice guideline of the American Thoracic Society and Infectious Diseases Society of America","volume":"200","author":"Metlay","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"S0899823X21004633_ref7","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1093\/ofid\/ofv133.1053","article-title":"Influence of a \u201cNo MRSA, No Pseudomonas \u201d comment to a respiratory culture in antibiotic utilization during the treatment of lower respiratory tract infection","volume":"2","author":"Mcbride","year":"2015","journal-title":"Open Forum Infect Dis"}],"updated-by":[{"DOI":"10.1017\/ice.2021.508","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000}}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0899823X21004633","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T08:17:12Z","timestamp":1663316232000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0899823X21004633\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,22]]},"references-count":10,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["S0899823X21004633"],"URL":"https:\/\/doi.org\/10.1017\/ice.2021.463","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,22]]},"assertion":[{"value":"\u00a9 The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}