{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:47:40Z","timestamp":1747172860570,"version":"3.40.5"},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T00:00:00Z","timestamp":1646611200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0899823X22000228_as1\"><jats:title>Objective:<\/jats:title><jats:p>Research on complications with peripherally inserted central catheter (PICC) lines that are placed for the treatment of prosthetic joint infection (PJI) after total hip arthroplasty (THA) and total knee arthroplasty (TKA) is scarce. We investigated the timing, frequency, and risk factors for PICC complications during treatment of PJI after THA and TKA.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22000228_as2\"><jats:title>Methods:<\/jats:title><jats:p>We retrospectively queried an institutional database for THA and TKA patients from January 2015 through December 2020 that developed a PJI and required PICC placement at an academic, tertiary-care referral center.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22000228_as3\"><jats:title>Results:<\/jats:title><jats:p>The study included 889 patients (48.3% female) with a mean age of 64.6 years (range, 18.7\u201395.2) who underwent 435 THAs and 454 TKAs that were revised for PJI. The cohort had 275 90-day ED visits (30.9%), and 51 (18.5%) were PICC related. The average time from discharge to PICC ED visit was 26.2 days (range, 0.3\u201389.4). The most common reasons for a 90-day ED visit were issues related to the joint replacement or wound site (musculoskeletal or MSK; n = 116, 42.2%) and PICC complaints (n = 51, 18.5%). A multivariable logistic regression demonstrated that non-White race (odds ratio [OR], 2.24; 95% confidence interval [CI], 1.24\u20134.04; <jats:italic>P<\/jats:italic> = .007) and younger age (OR, 0.98; 95% CI, 0.95\u20131.00; <jats:italic>P<\/jats:italic> = .035) were associated with PICC-related ED visits. Malposition\/readjustment (41.2%) and occlusion (35.3%) were the most common PICC complications leading to ED presentation.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22000228_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>PICC complications are common after PJI treatment, accounting for nearly 20% of 90-day ED visits.<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2022.22","type":"journal-article","created":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T09:03:43Z","timestamp":1646643823000},"page":"1853-1858","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["An analysis of 90-day emergency department visits after peripherally inserted central catheter (PICC) placement for prosthetic joint infection"],"prefix":"10.1017","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0907-1254","authenticated-orcid":false,"given":"Lefko T.","family":"Charalambous","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoe","family":"Hinton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1519-6566","authenticated-orcid":false,"given":"Billy I.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayden","family":"Case","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meredith","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Jiranek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7117-513X","authenticated-orcid":false,"given":"Jessica","family":"Seidelman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael P.","family":"Bolognesi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thorsten M.","family":"Seyler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2022,3,7]]},"reference":[{"key":"S0899823X22000228_ref5","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-016-0161-0"},{"key":"S0899823X22000228_ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-021-04191-y"},{"key":"S0899823X22000228_ref6","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2013.775"},{"key":"S0899823X22000228_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.medmal.2013.06.013"},{"key":"S0899823X22000228_ref2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1710926"},{"key":"S0899823X22000228_ref7","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2015.317"},{"key":"S0899823X22000228_ref8","doi-asserted-by":"publisher","DOI":"10.5301\/jva.5000389"},{"key":"S0899823X22000228_ref10","doi-asserted-by":"publisher","DOI":"10.3171\/2020.6.SPINE191477"},{"key":"S0899823X22000228_ref3","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky474"},{"key":"S0899823X22000228_ref9","doi-asserted-by":"publisher","DOI":"10.3928\/01477447-20200818-02"},{"key":"S0899823X22000228_ref1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis803"}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0899823X22000228","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T10:26:19Z","timestamp":1671013579000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0899823X22000228\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,7]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["S0899823X22000228"],"URL":"https:\/\/doi.org\/10.1017\/ice.2022.22","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"type":"print","value":"0899-823X"},{"type":"electronic","value":"1559-6834"}],"subject":[],"published":{"date-parts":[[2022,3,7]]},"assertion":[{"value":"\u00a9 The Author(s), 2022. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}