{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T12:42:25Z","timestamp":1792154545688,"version":"4.4.0"},"reference-count":39,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T00:00:00Z","timestamp":1678665600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0899823X22002562_as1\"><jats:title>Objectives:<\/jats:title><jats:p>We quantified the percentage of multidrug-resistant organism (MDRO) carriers among repatriated patients. We identified factors associated with MDRO carriage, and we evaluated the yield of MDRO detection per screened body site.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22002562_as2\"><jats:title>Design:<\/jats:title><jats:p>Retrospective cohort study.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22002562_as3\"><jats:title>Setting:<\/jats:title><jats:p>A tertiary-care center in Switzerland.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22002562_as4\"><jats:title>Patients:<\/jats:title><jats:p>Adult patients after a stay in a healthcare institution abroad.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22002562_as5\"><jats:title>Methods:<\/jats:title><jats:p>Patients were screened for MDRO carriage. Standard sites, including nose and throat, groins, and (since mid-2018) rectum, and risk-based sites (wounds, urine, tracheal secretion) were sampled. MDROs were defined as methicillin-resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (MRSA), vancomycin-resistant <jats:italic>Enterococcus<\/jats:italic> (VRE), extended-spectrum \u03b2-lactamase (ESBL)\u2013 and carbapenemase-producing Enterobacterales (CPE), multidrug-resistant (MDR) Enterobacterales, and MDR nonfermenting gram-negative rods. Risk factors for MDRO carriage were assessed using multivariate logistic regression.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22002562_as6\"><jats:title>Results:<\/jats:title><jats:p>Between May 2017 and April 2019, 438 patients were screened and 107 (24.4%) tested positive for an MDRO, predominantly ESBL-producing and MDR Enterobacterales. Risk factors for MDRO colonization were the length of stay in hospital abroad, antibiotic treatment with \u2018Watch\u2019 and \u2018Reserve\u2019 antibiotics, and region of hospitalization abroad. Rectal swabs had the highest yield for detecting patients with MDR intestinal bacteria, but nose\/throat and groins,\u00a0or wound samples were more sensitive for MRSA or nonfermenting gram-negative organisms, respectively.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22002562_as7\"><jats:title>Conclusions:<\/jats:title><jats:p>We identified risk factors for MDRO carriage and body sites with the highest yield for a specific MDRO, which might help to target screening and isolation and reduce screening costs.<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2022.256","type":"journal-article","created":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T11:18:51Z","timestamp":1678706331000},"page":"1281-1288","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":7,"title":["Identifying patients at high risk for multidrug-resistant organisms after hospitalization abroad"],"prefix":"10.1017","volume":"44","author":[{"given":"Tamara C","family":"Bopp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Marchesi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7510-837X","authenticated-orcid":false,"given":"Reto","family":"Zihlmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1532-2198","authenticated-orcid":false,"given":"Hugo","family":"Sax","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9028-0007","authenticated-orcid":false,"given":"Aline","family":"Wolfensberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,3,13]]},"reference":[{"key":"S0899823X22002562_ref10","first-page":"w14208","article-title":"Repatriations and 28-day mortality of ill and injured travellers: 12 years of experience in a Swiss emergency department","volume":"145","author":"Hasler","year":"2015","journal-title":"Swiss Med Wkly"},{"key":"S0899823X22002562_ref1","doi-asserted-by":"publisher","DOI":"10.1038\/nature06536"},{"key":"S0899823X22002562_ref2","unstructured":"2. 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Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided that no alterations are made and the original article is properly cited. The written permission of Cambridge University Press must be obtained prior to any commercial use and\/or adaptation of the article.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}