{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T11:14:19Z","timestamp":1776510859179,"version":"3.51.2"},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T00:00:00Z","timestamp":1678924800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0899823X22002720_as1\"><jats:title>Objective:<\/jats:title><jats:p>To describe the effect of a microbiology comment nudge on antibiotic use for asymptomatic bacteriuria (ASB).<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22002720_as2\"><jats:title>Design:<\/jats:title><jats:p>Single-center, before-and-after, quasi-experimental study.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22002720_as3\"><jats:title>Setting:<\/jats:title><jats:p>Community-based, public, not-for-profit teaching hospital in the southeastern United States.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22002720_as4\"><jats:title>Participants:<\/jats:title><jats:p>Adult inpatients with a positive urine culture and the absence of urinary tract infection signs and symptoms.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22002720_as5\"><jats:title>Intervention:<\/jats:title><jats:p>Implementation of a microbiology comment nudge on urine cultures.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22002720_as6\"><jats:title>Results:<\/jats:title><jats:p>In total, 204 patients were included in the study. Antibiotics were less likely to be continued beyond 72 hours in the postimplementation group: 57 (55%) of 104 versus 38 (38%) of 100 (<jats:italic>P<\/jats:italic> = .016). They were less likely to have antibiotics continued beyond 48 hours: 60 (58%) of 104 versus 43 (43%) of 100 (<jats:italic>P<\/jats:italic> = .036). They were also less likely to have antibiotics prescribed at discharge 35 (34%) of 104 versus 20 (20%) of 100 (<jats:italic>P<\/jats:italic> = .028). In addition, they had fewer total antibiotic days of therapy: 4 (IQR, 1\u20136) versus 1 (IQR, 0\u20136) (<jats:italic>P<\/jats:italic> = .022).<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X22002720_as7\"><jats:title>Conclusion:<\/jats:title><jats:p>Microbiology comment nudging may contribute to less antibiotic utilization in patients with ASB.<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2022.272","type":"journal-article","created":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T08:19:01Z","timestamp":1678954741000},"page":"1391-1395","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":9,"title":["Effect of microbiology comment nudging on antibiotic use in asymptomatic bacteriuria: A before-and-after quasi-experimental study"],"prefix":"10.1017","volume":"44","author":[{"given":"Madeline G.","family":"Belk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia D.","family":"Hammond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Callie C.","family":"Seales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan D.","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7656-1504","authenticated-orcid":false,"given":"Taylor D.","family":"Steuber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2023,3,16]]},"reference":[{"key":"S0899823X22002720_ref6","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3390\/pharmacy9030138","article-title":"Treatment of asymptomatic bacteriuria after implementation of an inpatient urine culture algorithm in the electronic medical record","volume":"9","author":"Osiemo","year":"2021","journal-title":"Pharmacy (Basel)"},{"key":"S0899823X22002720_ref11","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/phar.2201","article-title":"Duration of exposure to antipseudomonal \u03b2-lactam antibiotics in the critically ill and development of new resistance","volume":"39","author":"Teshome","year":"2019","journal-title":"Pharmacother"},{"key":"S0899823X22002720_ref1","doi-asserted-by":"crossref","first-page":"e83","DOI":"10.1093\/cid\/ciz021","article-title":"Clinical practice guideline for the management of asymptomatic bacteriuria: 2019 update by the Infectious Diseases Society of America","volume":"68","author":"Nicolle","year":"2019","journal-title":"Clin Infect Dis"},{"key":"S0899823X22002720_ref3","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1001\/jamainternmed.2019.2871","article-title":"Risk factors and outcomes associated with treatment of asymptomatic bacteriuria in hospitalized patients","volume":"179","author":"Petty","year":"2019","journal-title":"JAMA Intern Med"},{"key":"S0899823X22002720_ref9","doi-asserted-by":"crossref","first-page":"ofy162","DOI":"10.1093\/ofid\/ofy162","article-title":"Microbiology comment nudge improves pneumonia prescribing","volume":"5","author":"Musgrove","year":"2018","journal-title":"Open Forum Infect Dis"},{"key":"S0899823X22002720_ref7","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1093\/cid\/ciu010","article-title":"Reducing antimicrobial therapy for asymptomatic bacteruria among noncatheterized inpatients: a proof-of-concept study","volume":"58","author":"Leis","year":"2014","journal-title":"Clin Infect Dis"},{"key":"S0899823X22002720_ref12","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1093\/cid\/cis534","article-title":"The role of asympomatic bacteriuria in young women with recurrent urinary tract infections: to treat or not to treat?","volume":"55","author":"Cai","year":"2012","journal-title":"Clin Infect Dis"},{"key":"S0899823X22002720_ref8","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1001\/jamainternmed.2017.7290","article-title":"An implementation guide to reducing overtreatment of asymptomatic bacteruria","volume":"178","author":"Daniel","year":"2018","journal-title":"JAMA Int Med"},{"key":"S0899823X22002720_ref4","doi-asserted-by":"crossref","first-page":"392","DOI":"10.12788\/jhm.2892","article-title":"The use of clinical decision support in reducing diagnosis of and treatment of asymptomatic bacteriuria","volume":"13","author":"Keller","year":"2018","journal-title":"J Hosp Med"},{"key":"S0899823X22002720_ref2","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1097\/QCO.0000000000000019","article-title":"Asymptomatic bacteriuria","volume":"27","author":"Nicolle","year":"2014","journal-title":"Curr Opin Infect Dis"},{"key":"S0899823X22002720_ref13","first-page":"CD009534","article-title":"Leibovici. Antibiotics for asympomatic bacteriuria","volume":"4","author":"Trestioreanu","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"S0899823X22002720_ref10","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1017\/ice.2019.293","article-title":"Nudging in microbiology laboratory evaluation (NIMBLE): a scoping review","volume":"40","author":"Langford","year":"2019","journal-title":"Infect Control Hosp Epidemiol"},{"key":"S0899823X22002720_ref14","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1017\/ice.2018.100","article-title":"Modified reporting of positive urine cultures to reduce inappropriate treatment of asymptomatic bacteriuria among nonpregnant, noncatheterized inpatients: a randomized controlled trial","volume":"39","author":"Daley","year":"2018","journal-title":"Infect Control Hosp Epidemiol"},{"key":"S0899823X22002720_ref5","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1017\/ice.2015.281","article-title":"Treatment for positive urine cultures in hospitalized adults: a three medical center survey of prevalence and risk factors","volume":"37","author":"Grein","year":"2016","journal-title":"Infect Control Hosp Epidemiol"}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0899823X22002720","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T07:37:14Z","timestamp":1711957034000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0899823X22002720\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,16]]},"references-count":14,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["S0899823X22002720"],"URL":"https:\/\/doi.org\/10.1017\/ice.2022.272","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,16]]},"assertion":[{"value":"\u00a9 The Author(s), 2023. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}