{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:48:17Z","timestamp":1747172897888,"version":"3.40.5"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T00:00:00Z","timestamp":1689724800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0899823X23001484_as1\"><jats:title>Objective:<\/jats:title><jats:p>Determination of whether vascular catheter disinfecting antiseptic-containing caps alone are effective at decreasing microbial colonization of connectors compared to antiseptic-containing caps plus a 5-second alcohol manual disinfection.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X23001484_as2\"><jats:title>Setting:<\/jats:title><jats:p>The study was conducted in a 718-bed, tertiary-care, academic hospital.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X23001484_as3\"><jats:title>Patients:<\/jats:title><jats:p>A convenience sample of adult patients across intensive care units and acute care wards with peripheral and central venous catheters covered with antiseptic-containing caps.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X23001484_as4\"><jats:title>Methods:<\/jats:title><jats:p>Quality improvement study completed over 5 days. The standard-of-care group consisted of catheter connectors with antiseptic-containing caps cleaned with a 5-second alcohol wipe scrub prior to culture. The comparison group consisted of catheter connectors with antiseptic-containing caps without a 5-second alcohol wipe scrub prior to culture. The connectors were pressed directly onto blood agar plates and incubated. Plates were assessed for growth after 48-72 hours.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X23001484_as5\"><jats:title>Results:<\/jats:title><jats:p>In total, 356 catheter connectors were cultured: 165 in the standard-of-care group, 165 in the comparison group, and 26 catheters connectors without an antiseptic-containing cap, which were designated as controls. Overall, 18 catheter connectors (5.06%) yielded microbial growth. Of the 18 connectors with microbial growth, 2 (1.21%) were from the comparison group, 1 (0.61%) was from the standard-of-care group, and 15 were controls without an antiseptic-containing cap.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X23001484_as6\"><jats:title>Conclusions:<\/jats:title><jats:p>Bacterial colonization rates were similar between the catheter connectors cultured with antiseptic-containing caps alone and catheter connectors with antiseptic-containing caps cultured after a 5-second scrub with alcohol. This finding suggests that the use of antiseptic-containing caps precludes the need for additional disinfection.<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2023.148","type":"journal-article","created":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T10:20:27Z","timestamp":1689762027000},"page":"35-39","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Disinfection of vascular catheter connectors that are protected by antiseptic caps is unnecessary"],"prefix":"10.1017","volume":"45","author":[{"given":"Kelsey M.","family":"Fillman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4566-1905","authenticated-orcid":false,"given":"Jonathan H.","family":"Ryder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5079-4588","authenticated-orcid":false,"given":"Daniel M.","family":"Brailita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8946-8272","authenticated-orcid":false,"given":"Mark E.","family":"Rupp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8791-9719","authenticated-orcid":false,"given":"R. 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