{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:42:37Z","timestamp":1786999357933,"version":"build-2736575974"},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T00:00:00Z","timestamp":1728604800000},"content-version":"unspecified","delay-in-days":40,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2024,9]]},"abstract":"Abstract<\/jats:title>\n \n Purpose:<\/jats:title>\n Viral hemorrhagic fevers (VHFs), such as Ebola virus disease, Marburg virus disease, and Lassa fever, are associated with significant morbidity and mortality and the potential for person-to-person transmission. While most individuals in whom VHF is suspected will ultimately be diagnosed with a non-VHF illness, such patients may present to any United States healthcare facility (HCF) for initial evaluation; therefore, all HCFs must be prepared to evaluate and initiate care for suspect VHF patients, especially if they are acutely ill. Included within this evaluation is the ability to perform basic routine laboratory testing before VHF-specific diagnostic test results are available, as well as rapid malaria testing to assess for a common, dangerous \u201cVHF mimic.\u201d<\/jats:p>\n <\/jats:sec>\n \n Objective:<\/jats:title>\n To improve laboratory preparedness and readiness in the initial care of suspect VHF patients who may present to acute care hospitals.<\/jats:p>\n <\/jats:sec>\n \n Design:<\/jats:title>\n Plan-Do-Study-Act quality improvement model.<\/jats:p>\n <\/jats:sec>\n \n Setting:<\/jats:title>\n Frontline healthcare facilities and their clinical laboratories.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n We describe the development of a laboratory testing toolkit for a suspect VHF patient that can assist frontline HCFs in providing basic laboratory testing required for the care of these patients.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n The toolkit provides guidance on infection prevention and control, waste management, occupational health, laboratory test collection, processing, and resulting, in the context of suspect VHF patient evaluation.<\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n The toolkit is designed to be readily adapted by any frontline HCF in the US. With the guidance provided, facilities will be able to support safer initial evaluation of VHF suspects and ensure high-quality patient care.<\/jats:p>\n <\/jats:sec>","DOI":"10.1017\/ice.2024.143","type":"journal-article","created":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T03:02:40Z","timestamp":1728615760000},"page":"1043-1049","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":6,"title":["Enabling laboratory readiness and preparedness for the evaluation of suspected viral hemorrhagic fevers: development of a laboratory toolkit"],"prefix":"10.1017","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3603-8110","authenticated-orcid":false,"given":"Sarah E.","family":"Turbett","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9286-3548","authenticated-orcid":false,"given":"Jacob E.","family":"Lazarus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mia A.","family":"Nardini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph E.","family":"Braidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie A.","family":"Lane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen F.","family":"Searle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9664-6476","authenticated-orcid":false,"given":"Paul D.","family":"Biddinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8086-1123","authenticated-orcid":false,"given":"Erica S.","family":"Shenoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2024,10,11]]},"reference":[{"key":"S0899823X24001430_ref4","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6502a3"},{"key":"S0899823X24001430_ref12","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2003.69.6.0690589"},{"key":"S0899823X24001430_ref2","unstructured":"2. 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Updated April 9, 2020. 2023. https:\/\/www.cdc.gov\/malaria\/about\/distribution.html"},{"key":"S0899823X24001430_ref6","unstructured":"6. BinaxNOW Malaria Test Kit Product Instructions. 2019. https:\/\/ensur.invmed.com\/ensur\/broker\/ensurbroker.aspx?code=IN665000&cs=26709298"},{"key":"S0899823X24001430_ref14","unstructured":"14. Centers for Disease Control and Prevention (CDC). Malaria Diagnostic Tests. Updated January 12, 2023. 2023. https:\/\/www.cdc.gov\/malaria\/diagnosis_treatment\/diagnostic_tools.html"},{"key":"S0899823X24001430_ref15","unstructured":"15. Centers for Disease Control and Prevention (CDC). Guidance for U.S. Hospitals and Clinical Laboratories on Performing Routine Diagnostic Testing for Patients with Suspected Ebola Disease. Updated April, 20 2023. 2023. https:\/\/www.cdc.gov\/vhf\/ebola\/laboratory-personnel\/safe-specimen-management.html"},{"key":"S0899823X24001430_ref9","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-023-02847-1"},{"key":"S0899823X24001430_ref5","first-page":"1","article-title":"Malaria surveillance \u2014 United States, 2018","volume":"71","author":"Mace","year":"2022","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"S0899823X24001430_ref1","unstructured":"1. UK Health Security Agency. High consequence infectious diseases (HCID). Updated January 25, 2023. Accessed September 22, 2023, 2023. https:\/\/www.gov.uk\/guidance\/high-consequence-infectious-diseases-hcid"},{"key":"S0899823X24001430_ref13","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11050768"},{"key":"S0899823X24001430_ref17","unstructured":"17. Stone, V. Planning a Method Verification Study in Clinical Microbiology Labs. Updated January 11, 2022. 2023. https:\/\/asm.org\/Articles\/2022\/January\/Planning-a-Method-Verification-Study-in-Clinical-M"},{"key":"S0899823X24001430_ref8","unstructured":"8. Centers for Disease Control and Prevention (CDC). Strengthening Clinical Laboratories. Accessed October 3, 2023, 2023. https:\/\/www.cdc.gov\/csels\/dls\/strengthening-clinical-labs.html"},{"key":"S0899823X24001430_ref10","unstructured":"10. https:\/\/www.beckershospitalreview.com\/rankings-and-ratings\/hospitals-with-the-most-ed-visits-in-2022.html"},{"key":"S0899823X24001430_ref7","unstructured":"7. College of American Pathologists. Surveys and Anatomic Pathology Education Programs. 2023. https:\/\/documents.cap.org\/documents\/2023-cap-surveys-catalog.pdf"}],"container-title":["Infection Control & Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0899823X24001430","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T08:51:27Z","timestamp":1730710287000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0899823X24001430\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":17,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S0899823X24001430"],"URL":"https:\/\/doi.org\/10.1017\/ice.2024.143","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"\u00a9 The Author(s), 2024. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}