{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T02:46:12Z","timestamp":1792118772487,"version":"4.4.0"},"reference-count":10,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    In a propensity-matched cohort of adult cardiac or neurosurgical procedures (\n                    <jats:italic>n<\/jats:italic>\n                    = 1,342), infection was less frequent with continuous infusion (1.8%) versus intermittent cefazolin (2.4%), though the difference was statistically non-significant (\u22120.6%, 95% CI\u22122.3 to 1.1;\n                    <jats:italic>p<\/jats:italic>\n                    = 0.57). The 0% infection rate among cardiac cases receiving continuous cefazolin infusion warrants further investigation.\n                  <\/jats:p>","DOI":"10.1017\/ice.2025.10365","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T09:55:02Z","timestamp":1764755702000},"page":"195-198","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of cefazolin administered as a continuous or intermittent infusion for prophylaxis of surgical site infections in adult patients undergoing cardiac or neurologic surgery"],"prefix":"10.1017","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0406-0804","authenticated-orcid":false,"given":"Richard H.","family":"Drew","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00py81415","id-type":"ROR","asserted-by":"publisher"}],"name":"Duke University School of Medicine (Infectious Diseases)"},{"id":[{"id":"https:\/\/ror.org\/03wfqwh68","id-type":"ROR","asserted-by":"publisher"}],"name":"Campbell University College of Pharmacy & Health Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0650-4894","authenticated-orcid":false,"given":"Nicholas A.","family":"Turner","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00py81415","id-type":"ROR","asserted-by":"publisher"}],"name":"Duke University School of Medicine (Infectious Diseases)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8115-499X","authenticated-orcid":false,"given":"Elizabeth","family":"Keil","sequence":"additional","affiliation":[{"name":"HCA HealthONE Swedish"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Seidelman","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00py81415","id-type":"ROR","asserted-by":"publisher"}],"name":"Duke University School of Medicine (Infectious Diseases)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,12,3]]},"reference":[{"key":"S0899823X25103656_ref3","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp120568"},{"key":"S0899823X25103656_ref8","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofz360.1106"},{"key":"S0899823X25103656_ref1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.24075"},{"key":"S0899823X25103656_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.03.038"},{"key":"S0899823X25103656_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/phar.1689"},{"key":"S0899823X25103656_ref2","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2017.0904"},{"key":"S0899823X25103656_ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-019-0638-8"},{"key":"S0899823X25103656_ref9","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13123524"},{"key":"S0899823X25103656_ref10","unstructured":"10. RCT. R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. https:\/\/www.R-pproject.org\/."},{"key":"S0899823X25103656_ref6","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2015.03.026"}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0899823X25103656","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T02:39:20Z","timestamp":1792118360000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0899823X25103656\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,3]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S0899823X25103656"],"URL":"https:\/\/doi.org\/10.1017\/ice.2025.10365","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,3]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided that no alterations are made and the original article is properly cited. The written permission of Cambridge University Press or the rights holder(s) must be obtained prior to any commercial use and\/or adaptation of the article.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}