{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T05:58:06Z","timestamp":1775800686406,"version":"3.50.1"},"reference-count":33,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T00:00:00Z","timestamp":1742947200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0899823X25000443_as1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>An association between weekend\/off-hour care and unfavorable clinical outcomes has been observed, commonly called the \u201cweekend effect.\u201d In the present study, we examined whether there was a weekend effect associated with blood culture (BC) contamination, which can lead to inappropriate medical resource consumption.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X25000443_as2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a single-center retrospective observational study using data from BC tests performed on adult patients. The primary outcome was the incidence of BC contamination, which was compared between weekend and weekday sampling groups. In a multivariable logistic analysis, we evaluated the association between weekend sampling and the incidence of BC contamination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X25000443_as3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The analysis included 7,597 weekend and 50,655 weekday BC sets from 1 January 2013 to 31 December 2019. The proportion of BC contamination during the study period was 1.15% (87\/7,597) and 0.80% (405\/50,655) in the weekend and weekday groups, respectively. In the logistic regression analysis adjusted for blood sampling settings, weekend sampling was significantly associated with increased BC contamination (odds ratio, 1.36; 95% confidence interval, 1.06\u20131.71).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X25000443_as4\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This study highlighted a significant association between weekend blood sampling for BC and an increased incidence of contamination. To provide better-quality care, further studies evaluating the differences in staffing and blood collection processes on weekends and weekdays are warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/ice.2025.44","type":"journal-article","created":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T04:00:03Z","timestamp":1742961603000},"page":"629-634","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Weekend effect on blood culture contamination: an observational study at a university hospital in Japan"],"prefix":"10.1017","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0879-033X","authenticated-orcid":false,"given":"Kazuhiko","family":"Nakaharai","sequence":"first","affiliation":[{"name":"Jikei University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoichi","family":"Shinozaki","sequence":"additional","affiliation":[{"name":"Jikei University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taku","family":"Tamura","sequence":"additional","affiliation":[{"name":"Jikei University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Nakazawa","sequence":"additional","affiliation":[{"name":"Jikei University School of Medicine"},{"name":"Jikei University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Jikei University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,3,26]]},"reference":[{"key":"S0899823X25000443_ref31","doi-asserted-by":"publisher","DOI":"10.12788\/jhm.2815"},{"key":"S0899823X25000443_ref20","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00062-05"},{"key":"S0899823X25000443_ref32","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2017.430"},{"key":"S0899823X25000443_ref9","doi-asserted-by":"publisher","DOI":"10.1086\/673142"},{"key":"S0899823X25000443_ref5","doi-asserted-by":"publisher","DOI":"10.1086\/660096"},{"key":"S0899823X25000443_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2010.09.033"},{"key":"S0899823X25000443_ref16","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01555-07"},{"key":"S0899823X25000443_ref29","unstructured":"29. Public Health England. UK standards for microbiology investigations: investigation of blood cultures (for organisms other than Mycobacterium species) [Internet]. [cited 2024 May 6]. 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