{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:38:03Z","timestamp":1756463883882,"version":"3.40.4"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T00:00:00Z","timestamp":1739836800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0899823X2500008X_as1\"><jats:title>Objective:<\/jats:title><jats:p>To compare the risk and exposure-adjusted central line-associated bloodstream infection (CLABSI) rates between racial and ethnic groups.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X2500008X_as2\"><jats:title>Design:<\/jats:title><jats:p>Retrospective cohort study.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X2500008X_as3\"><jats:title>Setting:<\/jats:title><jats:p>15 network hospitals in Illinois and Michigan (Part of OSF HealthCare).<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X2500008X_as4\"><jats:title>Patients:<\/jats:title><jats:p>Patients of all age groups who had a central line inserted and removed during the same hospitalization between 01\/2018 and 06\/2023.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X2500008X_as5\"><jats:title>Methods:<\/jats:title><jats:p>CLABSI rates\/1000 Central line days of the four major racial and ethnic categories (Hispanic, non-Hispanic White [NHW], non-Hispanic Black [NHB], and non-Hispanic others) were analyzed by generalized Poisson regression. Confounding variables included in the regression model based on a directed acyclic graph and included age group, insurance class, language, ICU admission, diagnostic cohorts (obesity, diabetes, dialysis, cancer, neutropenia), and line usage (blood products, chemotherapy, total parenteral nutrition).<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X2500008X_as6\"><jats:title>Results:<\/jats:title><jats:p>27,674 central lines (244,889 catheter days) on 23,133 unique patients (median age 64 years, 8% pediatric patients) were included in the analysis. Overall, the CLABSI rate was 1.070\/1000 Central line days. 76% of the study population was NHW, 17% NHB, and 4% Hispanic. After adjusting for confounding variables, Hispanic patients had higher CLABSI rates than NHW (IRR 1.89, 95% CI 1.15\u20133.10, <jats:italic>P<\/jats:italic> = .013). No significant difference was observed in the CLABSI rates between NHW and NHB patients.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X2500008X_as7\"><jats:title>Conclusion:<\/jats:title><jats:p>Disparities in hospital-associated conditions persist even after controlling for patient-level risk factors and exposures, with Hispanic patients at the highest risk.<\/jats:p><\/jats:sec>","DOI":"10.1017\/ice.2025.8","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T10:25:23Z","timestamp":1739874323000},"page":"356-362","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Racial and ethnic disparities in central line-associated bloodstream infections (CLABSI) in hospitalized patients: a risk-adjusted analysis"],"prefix":"10.1017","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6494-1430","authenticated-orcid":false,"given":"Sandeep","family":"Tripathi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7917-8861","authenticated-orcid":false,"given":"Taylor","family":"Walter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2475-1071","authenticated-orcid":false,"given":"Jeremy","family":"McGarvey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,2,18]]},"reference":[{"key":"S0899823X2500008X_ref13","first-page":"58782","article-title":"Revisions to the standards for the classification of federal data on race and ethnicity","volume":"62","year":"1997","journal-title":"Fed Regist"},{"key":"S0899823X2500008X_ref4","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2021-054955"},{"key":"S0899823X2500008X_ref9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0282290"},{"key":"S0899823X2500008X_ref11","unstructured":"11. OSF Health Care. Facts and Figures. https:\/\/x.osfhealthcare.org\/patients-visitors\/about\/facts-figures. Published 2024. Accessed September 9, 2024."},{"key":"S0899823X2500008X_ref23","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2022-059688"},{"volume-title":"Unequal Treatment","year":"2002","key":"S0899823X2500008X_ref1"},{"key":"S0899823X2500008X_ref12","unstructured":"12. National Healthcare Safety Network (NSHN). Bloodstream Infection (BSI) Events. U.S Department of Health &Human Services. https:\/\/www.cdc.gov\/nhsn\/psc\/bsi\/index.html. Published 2024. 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