{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T03:49:19Z","timestamp":1793764159420,"version":"4.6.1"},"reference-count":29,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2026,5]]},"abstract":"Abstract<\/jats:title>\n \n Introduction:<\/jats:title>\n \n The spread of\n Candida auris<\/jats:italic>\n (\n C. auris<\/jats:italic>\n ), methicillin-resistant\n Staphylococcus aureus<\/jats:italic>\n (MRSA\n )<\/jats:italic>\n and various viruses in healthcare settings is of global concern. Far-UV-C\n 222<\/jats:sub>\n reduces the concentration of microorganisms in laboratory settings and can be used directly in patient care rooms at doses safe for human eyes and skin. The effectiveness of UV-C\n 222<\/jats:sub>\n inactivation of\n C. auris,<\/jats:italic>\n MRSA and T1 bacteriophage (a viral surrogate) in a hospital setting was studied.\n <\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n A partially blinded, cross-over study was conducted of two conditions: intervention, active UV and control, no UV.\n C. auris,<\/jats:italic>\n MRSA and T1 bacteriophage were inoculated and dried onto stainless steel disc carriers at two soil levels, (0.03% BSA and 5.0% CBS), and placed at 24 locations in two unoccupied, two-bed patient rooms. UV-C\n 222<\/jats:sub>\n luminaires were placed behind the head of each bed and one in the bathroom for both study rooms. Simultaneous 24-h exposures for both rooms were in random order. Pathogens were processed for cultures.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n UV-C\n 222<\/jats:sub>\n doses exposing the discs ranged from a low of 5 mJ\/cm\n 2<\/jats:sup>\n to high 637 mJ\/cm\n 2<\/jats:sup>\n . Under treatment conditions, MRSA showed a 1.0 log reduction in 0.03% soil,\n C. auris<\/jats:italic>\n showed a 2.6 log reduction in 0.03% soil and a 1.0 log reduction in 5.0% soil and T1 bacteriophage showed a 0.6 log reduction in 0.03% soil.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n \n In patient rooms, continuous UV-C\n 222<\/jats:sub>\n exposure showed decreased concentrations of\n C. auris<\/jats:italic>\n (low and high soil), MRSA (low soil), and T1 (low soil). Studies are needed to determine benefits in occupied settings.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1017\/ice.2026.10414","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T10:13:39Z","timestamp":1774520019000},"page":"509-516","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":5,"title":["Efficacy of continuous UV-C\n 222<\/sub>\n exposure of\n Candida auris,<\/i>\n methicillin-resistant\n Staphylococcus aureus,<\/i>\n and T1 bacteriophage at two soil levels in hospital patient rooms"],"prefix":"10.1017","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3453-4070","authenticated-orcid":false,"given":"Richard L.","family":"Vincent","sequence":"first","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0125-8639","authenticated-orcid":false,"given":"Stephanie H.","family":"Factor","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"},{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Rivera Boudla","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Atkinson","sequence":"additional","affiliation":[{"name":"MRD Lighting"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James J.","family":"McDevitt","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/047s2c258","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard C.","family":"Camins","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,3,26]]},"reference":[{"key":"S0899823X26104140_ref9","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1017\/ice.2017.239","article-title":"Relative resistance of the emerging fungal pathogen candida auris and other Candida species to killing by ultraviolet light","volume":"39","author":"Cadnum","year":"2018","journal-title":"Infect Control Hosp Epidemiol"},{"key":"S0899823X26104140_ref4","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/S0140-6736(16)31588-4","article-title":"Enhanced terminal room disinfection and acquisition and infection caused by multidrug-resistant organisms and Clostridium difficile (the benefits of enhanced terminal room disinfection study): a cluster-randomised, multicentre, crossover 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Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}