{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T03:34:12Z","timestamp":1793072052749,"version":"4.5.0"},"reference-count":20,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"},{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/tdm\/tdmrep-policy.json"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0899823X26104899_as1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the pathogen-specific diagnostic yield of rectal and groin screening sites in a hospital-based multidrug-resistant organism (MDRO) surveillance program.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X26104899_as2\">\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Prospective observational surveillance study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X26104899_as3\">\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Tertiary academic hospital in Northern Greece.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X26104899_as4\">\n                    <jats:title>Patients:<\/jats:title>\n                    <jats:p>Hospitalized patients undergoing active MDRO screening based on predefined infection prevention and control criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X26104899_as5\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A pathogen-focused analysis was conducted using data from a prospective MDRO surveillance program between October 2024 and January 2025. Screening swabs were obtained from the rectum and groin. Target organisms included multidrug-resistant (MDR)\n                      <jats:italic>Klebsiella pneumoniae, Pseudomonas aeruginosa<\/jats:italic>\n                      , vancomycin-resistant enterococci (VRE),\n                      <jats:italic>Candida auris<\/jats:italic>\n                      , and\n                      <jats:italic>Acinetobacter<\/jats:italic>\n                      spp. Pathogen-specific detection yields were calculated for each anatomical site.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X26104899_as6\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among 1,206 screening swabs, 308 (25.5%) were positive for at least one MDRO. Rectal swabs detected 95.8% of\n                      <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                      (K. pneumoniae) (92\/96), 100% of VRE (59\/59), and 66.7% of\n                      <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                      (46\/69). In contrast, 88.9% of Candida auris cases (24\/27) were identified exclusively from groin swabs. Reliance on rectal screening alone would have missed nearly 90% of\n                      <jats:italic>Candida auris<\/jats:italic>\n                      carriers, whereas groin-only screening would have failed to detect most K. pneumoniae and all VRE carriers.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0899823X26104899_as7\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      Anatomical site selection critically influences MDRO surveillance sensitivity. Rectal screening is optimal for MDROs colonizing the gastrointestinal tract, whereas groin sampling is essential for detecting\n                      <jats:italic>Candida auris<\/jats:italic>\n                      . Pathogen-targeted, site-specific surveillance strategies may substantially improve detection efficiency and optimize infection prevention efforts in high-prevalence hospital settings.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/ice.2026.10489","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T05:49:16Z","timestamp":1781761756000},"page":"774-777","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Rectal versus groin screening for multidrug-resistant organisms: pathogen-specific diagnostic yield in a tertiary-care hospital"],"prefix":"10.1017","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2629-1841","authenticated-orcid":false,"given":"Athena","family":"Myrou","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01q1jaw52","id-type":"ROR","asserted-by":"publisher"}],"name":"Aristotle University of Thessaloniki, AHEPA University General Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simeon","family":"Metallidis","sequence":"additional","affiliation":[{"name":"Aristotle University of Thessaloniki, AHEPA University General Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Savopoulos","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01q1jaw52","id-type":"ROR","asserted-by":"publisher"}],"name":"Aristotle University of Thessaloniki, AHEPA University General Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,6,18]]},"reference":[{"key":"S0899823X26104899_ref18","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-24140-2"},{"key":"S0899823X26104899_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30753-3"},{"key":"S0899823X26104899_ref10","first-page":"1732","article-title":"Changes in prevalence of health care\u2013associated infections in U.S. hospitals","volume":"387","author":"Magill","year":"2022","journal-title":"N Engl J Med"},{"key":"S0899823X26104899_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(18)30605-4"},{"key":"S0899823X26104899_ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-024-01513-2"},{"key":"S0899823X26104899_ref3","first-page":"555","article-title":"Evolution of multidrug-resistant Klebsiella pneumoniae in Greece","volume":"10","author":"Galani","year":"2022","journal-title":"Microorganisms"},{"key":"S0899823X26104899_ref5","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-024-04999-9"},{"key":"S0899823X26104899_ref4","doi-asserted-by":"publisher","DOI":"10.3947\/ic.2024.0060"},{"key":"S0899823X26104899_ref14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006290"},{"key":"S0899823X26104899_ref8","volume-title":"Guidelines on Core Components of Infection Prevention and Control Programmes at the National and Acute Health CareFacility Level","year":"2016"},{"key":"S0899823X26104899_ref16","first-page":"1160","article-title":"An outbreak due to Candida auris with prolonged colonization and candidemia","volume":"24","author":"Ruiz-Gait\u00e1n","year":"2018","journal-title":"Emerg Infect Dis"},{"key":"S0899823X26104899_ref19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x"},{"key":"S0899823X26104899_ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-023-04535-1"},{"key":"S0899823X26104899_ref15","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00029-17"},{"key":"S0899823X26104899_ref17","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-42522-2"},{"key":"S0899823X26104899_ref12","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics13060561"},{"key":"S0899823X26104899_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02724-0"},{"key":"S0899823X26104899_ref6","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11102770"},{"key":"S0899823X26104899_ref9","volume-title":"Management of multidrug-resistant organisms in healthcare settings, 2006","author":"Siegel","year":"2006"},{"key":"S0899823X26104899_ref11","first-page":"486","article-title":"Impact of infection control interventions on the spread of multidrug-resistant gram-negative bacteria in a Greek tertiary care hospital","volume":"43","author":"Tsakris","year":"2015","journal-title":"Am J Infect Control"}],"container-title":["Infection Control &amp; 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Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}