{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T01:57:40Z","timestamp":1784944660419,"version":"3.55.0"},"reference-count":42,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T00:00:00Z","timestamp":1676851200000},"content-version":"unspecified","delay-in-days":50,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nutr Sci"],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>Vitamin D deficiency is prevalent in patients with chronic spinal cord injury (SCI) and has been implicated as an aetiologic factor of osteoporosis and various skeletal and extra-skeletal issues in SCI patients. Few data were available regarding vitamin D status in patients with acute SCI or immediately assessed at hospital admission. This retrospective cross-sectional study evaluated vitamin D status in SCI patients at admission to a UK SCI centre in January\u2013December 2017. A total of 196 eligible patients with serum 25(OH)D concentration records at admission were recruited. The results found that 24 % were vitamin D deficient (serum 25(OH)D &lt; 25 nmol\/l), 57 % of the patients had serum 25(OH)D &lt; 50 nmol\/l. The male patients, patients admitted in the winter\u2013spring time (December\u2013May), and patients with serum sodium &lt; 135 mmol\/l or with non-traumatic causes had a significant higher prevalence of vitamin D deficiency than their counterparts (28 % males <jats:italic>v.<\/jats:italic> 11\u22c58 % females, <jats:italic>P<\/jats:italic> = 0\u22c502; 30\u22c52 % in winter\u2013spring <jats:italic>v.<\/jats:italic> 12\u22c59 % in summer\u2013autumn, <jats:italic>P<\/jats:italic> = 0\u22c5007; 32\u22c51 % non-traumatic <jats:italic>v.<\/jats:italic> 17\u22c56 % traumatic SCI, <jats:italic>P<\/jats:italic> = 0\u22c503; 38\u22c59 % low serum sodium <jats:italic>v.<\/jats:italic> 18\u22c58 % normal serum sodium, <jats:italic>P<\/jats:italic> = 0\u22c5010). There was a significant inverse association of serum 25(OH)D concentration with body mass index (BMI) (<jats:italic>r<\/jats:italic> = \u22120\u22c5311, <jats:italic>P<\/jats:italic> = 0\u22c5002), serum total cholesterol (<jats:italic>r<\/jats:italic> = \u22120\u22c5168, <jats:italic>P<\/jats:italic> = 0\u22c504) and creatinine concentrations (<jats:italic>r<\/jats:italic> = \u22120\u22c5162, <jats:italic>P<\/jats:italic> = 0\u22c502) that were also significant predictors of serum 25(OH)D concentration. Strategies for systematic screening and efficacy of vitamin D supplementation in SCI patients need to be implemented and further investigated to prevent the vitamin D deficiency-related chronic complications.<\/jats:p>","DOI":"10.1017\/jns.2023.12","type":"journal-article","created":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T09:23:00Z","timestamp":1676884980000},"source":"Crossref","is-referenced-by-count":6,"title":["Prevalence of vitamin D deficiency in patients with spinal cord injury at admission: a single-centred study in the UK"],"prefix":"10.1017","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3975-5684","authenticated-orcid":false,"given":"Samford","family":"Wong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2225-7256","authenticated-orcid":false,"given":"Honglin","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shashivadan P.","family":"Hirani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina","family":"Gainullina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"Ussef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Graham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,2,20]]},"reference":[{"key":"S2048679023000125_ref2","unstructured":"2. 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