{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:15:36Z","timestamp":1785420936022,"version":"3.56.0"},"reference-count":43,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"unspecified","delay-in-days":307,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nutr Sci"],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Dietary fibre can modify colostrum and milk composition in sows. Bile acids (BA) aid in fat digestion and lipid absorption and are important signalling molecules for the digestive tract. The aim of this study was to determine BA concentration in colostrum from sows fed two different sources of dietary fibre during gestation and lactation and from the intestinal digesta of their 4-6-days-old suckling offspring. Twenty sows were fed diets enriched with either 15% high-fermentable sugar beet pulp (SBP,\n                    <jats:italic>n<\/jats:italic>\n                    = 10) or 15% low-fermentable lignocellulose (LNC,\n                    <jats:italic>n<\/jats:italic>\n                    = 10). Sow colostrum, piglet gallbladder content, ileum and colon digesta were assessed for BA using high-performance liquid chromatography coupled to triple-quadrupole mass spectrometry. In colostrum, lithocholic acid and oxolithocholic acid were higher in sows fed SBP vs. LNC (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.005 and\n                    <jats:italic>p<\/jats:italic>\n                    = 0.003, respectively), while 3\u03b1,7\u03b1,12\u03b1-trihydroxycholestanoic acid and glycohyodeoxycholic acid were higher in colostrum from sows fed LNC vs. SBP (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.039,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.002, respectively). In the piglet bile, cholic acid and taurodeoxycholic acid were higher in SBP vs. LNC group (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.02,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.001, respectively), while taurochenodeoxycholic acid was higher in LNC vs. SBP group (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.035). In the piglet ileum digesta, lithocholic acid was higher in SBP vs. LNC (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.015). In the piglet colon digesta, lithocholic acid and ursodeoxycholic acid were higher in SBP vs. LNC (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.001 and\n                    <jats:italic>p<\/jats:italic>\n                    = 0.007, respectively). Addition of specific dietary fibres to sow diets differentially influences the BA in colostrum. Dietary fibres in sow diets can impact on the intestinal BA composition in piglets with a possible consequence on the digestive physiology and health in the offspring.\n                  <\/jats:p>","DOI":"10.1017\/jns.2025.10050","type":"journal-article","created":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T06:35:12Z","timestamp":1762238112000},"source":"Crossref","is-referenced-by-count":0,"title":["Fibre composition in sow diets influences bile acid profile in colostrum and in intestinal digesta of their new-born suckling piglets"],"prefix":"10.1017","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0831-4077","authenticated-orcid":false,"given":"\u0141ukasz Marcin","family":"Grze\u015bkowiak","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/046ak2485","id-type":"ROR","asserted-by":"publisher"}],"name":"Freie Universit\u00e4t Berlin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio Rodolfo","family":"Ipharraguerre","sequence":"additional","affiliation":[{"name":"University of Kiel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Rimbach","sequence":"additional","affiliation":[{"name":"University of Kiel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilfried","family":"Vahjen","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/046ak2485","id-type":"ROR","asserted-by":"publisher"}],"name":"Freie Universit\u00e4t Berlin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Zentek","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/046ak2485","id-type":"ROR","asserted-by":"publisher"}],"name":"Freie Universit\u00e4t Berlin"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,11,4]]},"reference":[{"key":"S2048679025100505_ref29","doi-asserted-by":"publisher","DOI":"10.1002\/path.4983"},{"key":"S2048679025100505_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2020.e03717"},{"key":"S2048679025100505_ref36","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01765-07"},{"key":"S2048679025100505_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(98)80255-9"},{"key":"S2048679025100505_ref9","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00488-10"},{"key":"S2048679025100505_ref19","unstructured":"19. GfE. Empfehlungen zur Energie- und N\u00e4hrstoffversorgung von Schweinen. Frankfurt: DLG Verlag. Published online 2006."},{"key":"S2048679025100505_ref22","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-32107-9"},{"key":"S2048679025100505_ref43","doi-asserted-by":"publisher","DOI":"10.1016\/S0377-8401(97)00009-6"},{"key":"S2048679025100505_ref39","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00043.2007"},{"key":"S2048679025100505_ref12","doi-asserted-by":"publisher","DOI":"10.1017\/S1751731114000950"},{"key":"S2048679025100505_ref18","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2022.2083417"},{"key":"S2048679025100505_ref11","doi-asserted-by":"publisher","DOI":"10.1128\/jb.00180-23"},{"key":"S2048679025100505_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/tas\/txae062"},{"key":"S2048679025100505_ref17","unstructured":"17. Grze\u015bkowiak, \u0141M , Martinez-Vallespin, B , Wessels, AG , et al. Fiber composition in sows\u2019 diets influences bile acid profile in colostrum. In: Proceedings of the 25th Congress of the European Society of Veterinary and Comparative Nutrition. ; 2023:130."},{"key":"S2048679025100505_ref31","doi-asserted-by":"publisher","DOI":"10.2741\/3399"},{"key":"S2048679025100505_ref40","doi-asserted-by":"publisher","DOI":"10.1159\/000007469"},{"key":"S2048679025100505_ref38","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00338.2003"},{"key":"S2048679025100505_ref33","doi-asserted-by":"publisher","DOI":"10.1007\/s00284-020-01903-w"},{"key":"S2048679025100505_ref27","first-page":"1165","article-title":"Simultaneous determination of five bile acids as potential biomarkers for Alzheimer\u2019s disease in mouse brain and plasma","volume":"37","author":"Koike","year":"2021","journal-title":"Anal Sci Int J Japan Soc Anal Chem."},{"key":"S2048679025100505_ref28","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13201"},{"key":"S2048679025100505_ref4","doi-asserted-by":"publisher","DOI":"10.1080\/00365520310002913"},{"key":"S2048679025100505_ref35","doi-asserted-by":"publisher","DOI":"10.1094\/CCHEM.2003.80.3.260"},{"key":"S2048679025100505_ref37","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M075143"},{"key":"S2048679025100505_ref30","doi-asserted-by":"publisher","DOI":"10.5604\/01.3001.0010.5493"},{"key":"S2048679025100505_ref32","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3762(83)90005-6"},{"key":"S2048679025100505_ref14","volume-title":"The Gestating and Lactating Sow","author":"Hurley","year":"2015"},{"key":"S2048679025100505_ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-023-12987-2"},{"key":"S2048679025100505_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-009-0057-8"},{"key":"S2048679025100505_ref8","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2022.2083417"},{"key":"S2048679025100505_ref5","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.3945\/jn.113.177865","article-title":"Bile acids induce glucagon-like peptide 2 secretion with limited effects on intestinal adaptation in early weaned pigs","volume":"143","author":"Ipharraguerre","year":"2013","journal-title":"J Nutr."},{"key":"S2048679025100505_ref23","doi-asserted-by":"publisher","DOI":"10.3390\/nu15102299"},{"key":"S2048679025100505_ref34","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2008.07.007"},{"key":"S2048679025100505_ref25","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2018.1518554"},{"key":"S2048679025100505_ref42","first-page":"3068","article-title":"Flaxseed meal and oat hulls supplementation modulates growth performance, blood lipids, intestinal fermentation, bile acids, and neutral sterols in growing pigs fed corn\u2013soybean meal\u2013based diets","volume":"95","author":"Ndou","year":"2017","journal-title":"J Anim Sci."},{"key":"S2048679025100505_ref1","doi-asserted-by":"publisher","DOI":"10.1017\/S1466252322000081"},{"key":"S2048679025100505_ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00284-022-02848-y"},{"key":"S2048679025100505_ref41","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4274(01)00464-7"},{"key":"S2048679025100505_ref6","doi-asserted-by":"publisher","DOI":"10.1093\/jas\/sky327"},{"key":"S2048679025100505_ref16","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.202200677"},{"key":"S2048679025100505_ref20","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix567"},{"key":"S2048679025100505_ref21","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8010142"},{"key":"S2048679025100505_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2022.100697"},{"key":"S2048679025100505_ref2","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R500013-JLR200"}],"container-title":["Journal of Nutritional Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S2048679025100505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T06:35:26Z","timestamp":1762238126000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S2048679025100505\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":43,"alternative-id":["S2048679025100505"],"URL":"https:\/\/doi.org\/10.1017\/jns.2025.10050","relation":{},"ISSN":["2048-6790"],"issn-type":[{"value":"2048-6790","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"e79"}}