{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:07:47Z","timestamp":1785424067854,"version":"3.56.0"},"reference-count":39,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"unspecified","delay-in-days":21,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nutr Sci"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Dietary magnesium (Mg) is a potentially modifiable factor in preventing dementia, but current evidence supporting this remains insufficient and inconclusive. This study aimed to determine whether dietary Mg is associated with the risk of dementia among middle-aged and older people. Participants of this 8-year cohort study were 13,032 community-dwelling individuals aged 40\u201374 years. Dietary data were collected using a validated food frequency questionnaire in 2011\u20132013. Mg intake was adjusted for energy intake using the residual method. The outcome was newly diagnosed dementia determined using Japan\u2019s long-term care insurance database. Covariates included demographic characteristics, body size, lifestyles, and disease histories. Cox proportional hazard models were used to determine adjusted hazard ratios (HRs). The mean age of participants was 59.0 years. Dementia occurred in 148 males and 138 females. Lower quartiles of energy-adjusted Mg intake were associated with a higher risk of dementia (\n                    <jats:italic>P<\/jats:italic>\n                    for trend = 0.0410) in males, with the lowest quartile (Q1) having an elevated risk of dementia (HR = 1.73, 95% CI:1.07\u20132.83) compared to the highest quartile (Q4, reference); however, this association was not found in females. In a subgroup analysis by disease history in males, the HR of Q1 was attenuated in both subgroups; HR was 1.52 (95% CI:0.74\u20133.11) in those with a disease history and 1.40 (95% CI:0.73\u20132.69) in those without. In conclusion, low dietary Mg intake is associated with increased dementia risk in middle-aged and older Japanese males. However, this association may be partly attributable to underlying disease history.\n                  <\/jats:p>","DOI":"10.1017\/jns.2025.10075","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T06:26:38Z","timestamp":1769063198000},"source":"Crossref","is-referenced-by-count":1,"title":["Dietary magnesium intake and dementia risk in community-dwelling people aged 40\u201374 years: an 8-year cohort study"],"prefix":"10.1017","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7289-3037","authenticated-orcid":false,"given":"Irina","family":"Bulycheva","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04ww21r56","id-type":"ROR","asserted-by":"publisher"}],"name":"Niigata University Graduate School of Medical and Dental Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumi","family":"Watanabe","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04ww21r56","id-type":"ROR","asserted-by":"publisher"}],"name":"Niigata University Graduate School of Medical and Dental Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaori","family":"Kitamura","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04ww21r56","id-type":"ROR","asserted-by":"publisher"}],"name":"Niigata University Graduate School of Medical and Dental Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3665-9996","authenticated-orcid":false,"given":"Keiko","family":"Kabasawa","sequence":"additional","affiliation":[{"name":"Niigata University Graduate School of Medical and Dental Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiko","family":"Saito","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04ww21r56","id-type":"ROR","asserted-by":"publisher"}],"name":"Niigata University Graduate School of Medical and Dental Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akemi","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Niigata University of Rehabilitation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosaku","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Niigata University of Rehabilitation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rieko","family":"Oshiki","sequence":"additional","affiliation":[{"name":"Niigata University of Rehabilitation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ribeka","family":"Takachi","sequence":"additional","affiliation":[{"name":"Nara Women\u2019s University Graduate School of Humanities and Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichiro","family":"Tsugane","sequence":"additional","affiliation":[{"name":"International University of Health and Welfare Graduate School of Public Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Yamazaki","sequence":"additional","affiliation":[{"name":"Niigata Prefectural Government"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Niigata University Graduate School of Medical and Dental Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8618-7632","authenticated-orcid":false,"given":"Kazutoshi","family":"Nakamura","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04ww21r56","id-type":"ROR","asserted-by":"publisher"}],"name":"Niigata University Graduate School of Medical and Dental Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,1,22]]},"reference":[{"key":"S204867902510075X_ref31","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00012.2014"},{"key":"S204867902510075X_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(21)00249-8"},{"key":"S204867902510075X_ref29","doi-asserted-by":"publisher","DOI":"10.3945\/jn.109.117747"},{"key":"S204867902510075X_ref5","first-page":"276","article-title":"Barbagallo M nutritional prevention of cognitive decline and dementia","volume":"89","author":"Dominguez","year":"2018","journal-title":"Acta Biomed"},{"key":"S204867902510075X_ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2012.04061.x"},{"key":"S204867902510075X_ref15","unstructured":"15. Report of the Subdivision on Resources the Council for Science and Technology Ministry of Education, Culture, Sports, Science, and Technology. Standard Tables of Food Composition in Japan 2010. Tokyo: Official Gazette Cooperation of Japan; 2010. 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