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Using pre-defined keywords, online databases (PubMed, Scopus, Web of Science Core Collection, and Google Scholar) were searched for relevant articles, published from inception up to February 2024. The outcomes included C-reactive protein (CRP), tumour necrosis factor-\u03b1 (TNF-\u03b1), interleukin-6 (IL-6), interleukin-1 beta (IL-1\u03b2), total antioxidant capacity (TAC), malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione peroxidase (GPX). Analyses of subgroups, linear, and non-linear associations were also carried out. Out of 1264 records initially retrieved, 38 RCTs were included. Supplementation with green tea improved the following indicators: IL-1\u03b2 (weighted mean difference (WMD): \u22120.10 pg\/mL; 95% CI: \u22120.15, -0.06), MDA (WMD: \u22120.40 mcmol\/L; 95 % CI: \u22120.63, \u22120.18), TAC (WMD: 0.09 mmol\/L; 95% CI: 0.05, 0.13), SOD (WMD: 17.21 u\/L; 95% CI: 3.24, 31.19), and GPX (WMD: 3.90 u\/L; 95% CI: 1.85, 5.95); but failed to improve others, including CRP (WMD: 0.01 mg\/L; 95% CI: \u22120.14, 0.15), IL-6 (WMD: \u22120.34 pg\/mL; 95% CI:\u22120.94, 0.26), and TNF-\u03b1 (WMD: \u22120.07 pg\/mL; 95% CI: \u22120.42, 0.28). Supplementation with green tea can improve the body\u2019s oxidative status. However, the results showed no significant effect of green tea on inflammatory markers, except for IL-1\u03b2. Further studies are needed to determine the effectiveness of green tea, particularly on inflammatory status.<\/jats:p>","DOI":"10.1017\/jns.2025.13","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T12:43:22Z","timestamp":1741956202000},"source":"Crossref","is-referenced-by-count":10,"title":["Effects of green tea supplementation on antioxidant status and inflammatory markers in adults: a grade-assessed systematic review and dose-response meta-analysis of randomised controlled trials"],"prefix":"10.1017","volume":"14","author":[{"given":"Mohammad 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