{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T08:25:33Z","timestamp":1768292733826,"version":"3.49.0"},"reference-count":76,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T00:00:00Z","timestamp":1584489600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Smok Cessat"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1834261220000134_sec_a1\" sec-type=\"other\"><jats:title>Objectives<\/jats:title><jats:p>Combined smoking and heavy drinking is a significant health burden. Varenicline, an efficacious tobacco pharmacotherapy that also shows promise for drinking, has yielded mixed results among heavy-drinking smokers. This pilot study investigated integrated tobacco and alcohol counselling plus varenicline for this vulnerable group.<\/jats:p><\/jats:sec><jats:sec id=\"S1834261220000134_sec_a2\" sec-type=\"other\"><jats:title>Design<\/jats:title><jats:p>Twelve-week parallel, randomized controlled pilot trial of two behavioural interventions in combination with open-label varenicline. Participants were randomized using computer-generated tables, stratified by sex.<\/jats:p><\/jats:sec><jats:sec id=\"S1834261220000134_sec_a3\" sec-type=\"other\"><jats:title>Setting<\/jats:title><jats:p>Outpatient academic medical centre research clinic.<\/jats:p><\/jats:sec><jats:sec id=\"S1834261220000134_sec_a4\" sec-type=\"other\"><jats:title>Participants<\/jats:title><jats:p>Volunteers who reported smoking and heavy drinking and sought tobacco or alcohol treatment (<jats:italic>N<\/jats:italic> = 26).<\/jats:p><\/jats:sec><jats:sec id=\"S1834261220000134_sec_a5\" sec-type=\"other\"><jats:title>Intervention<\/jats:title><jats:p>(1) Integrated tobacco + alcohol counselling (INT; <jats:italic>n<\/jats:italic> = 13) or (2) counselling focused on their presenting concern (i.e., tobacco or alcohol) (SINGLE; <jats:italic>n<\/jats:italic> = 13), plus varenicline (2 mg) for 12 weeks.<\/jats:p><\/jats:sec><jats:sec id=\"S1834261220000134_sec_a6\" sec-type=\"other\"><jats:title>Main outcomes<\/jats:title><jats:p>Feasibility\/acceptability, smoking quit rates and heavy drinking.<\/jats:p><\/jats:sec><jats:sec id=\"S1834261220000134_sec_a7\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>INT feasibility\/acceptability was high among men but not women. More participants quit smoking in INT than SINGLE. This outcome was only in men, not significant, but had a medium effect size. Both conditions yielded significant drinking reductions.<\/jats:p><\/jats:sec><jats:sec id=\"S1834261220000134_sec_a8\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>Integrated tobacco and alcohol behavioural counselling plus varenicline may be feasible and promote smoking cessation among men who smoke and drink heavily, but a larger sample is needed to replicate this finding.<\/jats:p><\/jats:sec>","DOI":"10.1017\/jsc.2020.13","type":"journal-article","created":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T05:35:55Z","timestamp":1584509755000},"page":"119-127","source":"Crossref","is-referenced-by-count":6,"title":["An integrated behavioural intervention combined with varenicline for heavy-drinking smokers: a randomized pilot study"],"prefix":"10.1017","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9410-2830","authenticated-orcid":false,"given":"Lisa M.","family":"Fucito","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ran","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie S.","family":"O'Malley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tess H.","family":"Hanrahan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jolomi T.","family":"Ikomi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srinivas","family":"Muvvala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen M.","family":"Carroll","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralitza","family":"Gueorguieva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2020,3,18]]},"reference":[{"key":"S1834261220000134_ref28","doi-asserted-by":"publisher","DOI":"10.1111\/acer.13396"},{"key":"S1834261220000134_ref24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.1991.tb01879.x"},{"key":"S1834261220000134_ref61","doi-asserted-by":"publisher","DOI":"10.1037\/a0030992"},{"key":"S1834261220000134_ref62","doi-asserted-by":"publisher","DOI":"10.1007\/s40429-016-0081-3"},{"key":"S1834261220000134_ref76","doi-asserted-by":"publisher","DOI":"10.15288\/jsad.2014.75.415"},{"key":"S1834261220000134_ref73","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2008.03.009"},{"key":"S1834261220000134_ref65","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2016.07.013"},{"key":"S1834261220000134_ref72","first-page":"371","article-title":"The recovery spectrum: From self-change to seeking treatment","volume":"33","author":"Tucker","year":"2011","journal-title":"Alcohol Research and Health"},{"key":"S1834261220000134_ref63","first-page":"133","article-title":"A stage model of behavioral therapies research: Getting started and moving on from stage 1","volume":"8","author":"Rounsaville","year":"2001","journal-title":"Clinical Psychology: Science and Practice"},{"key":"S1834261220000134_ref60","doi-asserted-by":"publisher","DOI":"10.1093\/ntr\/ntr258"},{"key":"S1834261220000134_ref59","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2004.04.024"},{"key":"S1834261220000134_ref56","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.71"},{"key":"S1834261220000134_ref29","doi-asserted-by":"publisher","DOI":"10.1037\/a0012717"},{"key":"S1834261220000134_ref55","doi-asserted-by":"publisher","DOI":"10.1037\/0893-164X.22.2.230"},{"key":"S1834261220000134_ref54","doi-asserted-by":"publisher","DOI":"10.1037\/a0023033"},{"key":"S1834261220000134_ref53","doi-asserted-by":"publisher","DOI":"10.1007\/BF02246162"},{"key":"S1834261220000134_ref64","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsat.2006.01.003"},{"key":"S1834261220000134_ref51","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0b013e3282f75e91"},{"key":"S1834261220000134_ref49","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.15.1561"},{"key":"S1834261220000134_ref38","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(20000215)85:4<498::AID-IJC9>3.0.CO;2-F"},{"key":"S1834261220000134_ref7","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.10.5.360"},{"key":"S1834261220000134_ref66","doi-asserted-by":"publisher","DOI":"10.15288\/jsa.2003.64.858"},{"key":"S1834261220000134_ref18","unstructured":"First, M. 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