{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T21:52:29Z","timestamp":1768686749881,"version":"3.49.0"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2018,11,6]],"date-time":"2018-11-06T00:00:00Z","timestamp":1541462400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"},{"start":{"date-parts":[[2018,11,6]],"date-time":"2018-11-06T00:00:00Z","timestamp":1541462400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Acta Neuropsychiatr."],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0924270818000297_abs1\" sec-type=\"objectives\"><jats:title>Objectives<\/jats:title><jats:p>Electroconvulsive therapy (ECT) is a safe and validated technique used to treat various psychiatric conditions. It triggers an artificially-induced seizure. This seizure is defined using several parameters such as the amount of energy, duration, frequency, pulse width and intensity. Efficacy and adverse events depend on the amount of energy delivered. Due to technical control, the amount of energy delivered by our unit\u2019s ECT device was limited to 614 mC, 60% of the maximum possible output of the device. We wondered if lowering the dose would lead to better seizure quality among maintenance ECT patients.<\/jats:p><\/jats:sec><jats:sec id=\"S0924270818000297_abs2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>We assessed seizure quality based on the EEG, using a validated tool created by MacPherson. Two evaluators independently rated the seizures. Pre- and post-control scores were compared using Student\u2019s <jats:italic>t<\/jats:italic>-test for paired samples.<\/jats:p><\/jats:sec><jats:sec id=\"S0924270818000297_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>We analysed data from 15 patients. Mean age was 65 years old. Twelve had depressive disorder, two had schizophrenia and one had schizo-affective disorder. Mean duration of seizure before control was 41.1 s [95% confidence interval (95CI)=26.1, 51.1]. The mean MacPherson\u2019s score was 20.3 (95CI=16.2, 24.4). After control, the mean MacPherson\u2019s score was 28.2 (23.1, 33.3), showing a significant difference with the pre-control dataset (<jats:italic>p<\/jats:italic>=0.032; <jats:italic>t<\/jats:italic>=\u22122.4; df=14). Specifically, peak mid-ictal amplitude increased from 6.9 (95CI=5.1, 8.7) to 10.0 (95CI=7.2, 12.8). Other sub-scores remained unchanged.<\/jats:p><\/jats:sec><jats:sec id=\"S0924270818000297_abs4\" sec-type=\"conclusion\"><jats:title>Conclusion<\/jats:title><jats:p>Lowering the energy delivered led to an overall increase of seizure quality among our sample. This highlights the necessity and utility of retitration during ECT maintenance, possibly leading to better management of our patients.<\/jats:p><\/jats:sec>","DOI":"10.1017\/neu.2018.29","type":"journal-article","created":{"date-parts":[[2018,11,6]],"date-time":"2018-11-06T10:43:46Z","timestamp":1541501026000},"page":"52-55","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":5,"title":["Reconsidering the seizure threshold? A retrospective study about seizure quality among patients with maintenance ECT"],"prefix":"10.1017","volume":"31","author":[{"given":"Simon","family":"Taib","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Levy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Arbus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Schmitt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine","family":"Yrondi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2018,11,6]]},"reference":[{"key":"S0924270818000297_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S0013-7006(17)30055-6"},{"key":"S0924270818000297_ref9","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0b013e31815f65b9"},{"key":"S0924270818000297_ref4","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0b013e3181e48165"},{"key":"S0924270818000297_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.psc.2016.04.004"},{"key":"S0924270818000297_ref7","doi-asserted-by":"publisher","DOI":"10.1097\/00124509-200203000-00015"},{"key":"S0924270818000297_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2010.02.134"},{"key":"S0924270818000297_ref14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199303253281204"},{"key":"S0924270818000297_ref11","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000274"},{"key":"S0924270818000297_ref10","doi-asserted-by":"publisher","DOI":"10.1097\/00124509-200412000-00002"},{"key":"S0924270818000297_ref6","doi-asserted-by":"publisher","DOI":"10.1177\/0004867417743343"},{"key":"S0924270818000297_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12705-5"},{"key":"S0924270818000297_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2008.03.001"},{"key":"S0924270818000297_ref1","volume-title":"The practice of electroconvulsive therapy: recommendations for treatment, training, and privileging (a task force report of the American Psychiatric Association)","year":"2008"},{"key":"S0924270818000297_ref8","first-page":"138","article-title":"The \u2018half-age\u2019 stimulation strategy for ECT dosing","volume":"12","author":"Petrides","year":"1996","journal-title":"Convuls Ther"},{"key":"S0924270818000297_ref15","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.57.5.438"}],"container-title":["Acta Neuropsychiatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0924270818000297","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T19:44:51Z","timestamp":1555098291000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0924270818000297\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,6]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["S0924270818000297"],"URL":"https:\/\/doi.org\/10.1017\/neu.2018.29","relation":{},"ISSN":["0924-2708","1601-5215"],"issn-type":[{"value":"0924-2708","type":"print"},{"value":"1601-5215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,6]]},"assertion":[{"value":"\u00a9 Scandinavian College of Neuropsychopharmacology 2018\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}