{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:54:28Z","timestamp":1790618068649,"version":"4.1.0"},"reference-count":45,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2019,10,14]],"date-time":"2019-10-14T00:00:00Z","timestamp":1571011200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"},{"start":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T00:00:00Z","timestamp":1566864000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Acta Neuropsychiatr."],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0924270819000358_as1\" sec-type=\"other\"><jats:title>Objective:<\/jats:title><jats:p>Deep brain stimulation (DBS) was approved by Food and Drug Administration for Parkinson\u2019s disease, essential tremor, primary generalised or segmental dystonia and obsessive-compulsive disorder (OCD) treatment. The exact mechanism of DBS remains unclear which causes side effects. The aim of this review was to assess variables causing stimulation-induced chronic psychiatric\/personality-changing side effects.<\/jats:p><\/jats:sec><jats:sec id=\"S0924270819000358_as2\" sec-type=\"other\"><jats:title>Methods:<\/jats:title><jats:p>The analysis of scientific database (PubMed, Cochrane Library, EMBASE) was conducted. The included articles had to be research study or case report and DBS to be conducted in therapeutic purposes. The researches with mental disorders in patients\u2019 medical histories were excluded.<\/jats:p><\/jats:sec><jats:sec id=\"S0924270819000358_as3\" sec-type=\"other\"><jats:title>Results:<\/jats:title><jats:p>Seventeen articles were used in the review. In the group of movement disorders the characteristic of side effects was strongly related to the placement of the electrode implantation. Tiredness\/fatigue was correlated with DBS in thalamus. Implantations in subthalamic nucleus were mostly followed by affective side effects such as depression or suicide. The higher voltage of electrode was connected with more severe depression after implantation. The analysis of affective disorder contained only three articles \u2013 two about OCD and one about depression. Forgetfulness and word-finding problems as activities connected with cognition may be an inevitable side effect if obsessive thoughts are to be inhibited.<\/jats:p><\/jats:sec><jats:sec id=\"S0924270819000358_as4\" sec-type=\"other\"><jats:title>Conclusion:<\/jats:title><jats:p>DBS of subthalamic nucleus should be seen as the most hazardous place of implantation. 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