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Compared to patients without infection, patients with infection showed significantly more often visual hallucinations (28.6% vs 8.1%), confusion (36.9% vs 11.3%), an acute onset of illness (88.5% vs 59.6%) and less often depression (13.1% vs 35.5%) and a delusional content related to the pandemic (29.5% vs 78.3%). Both groups had an equally favourable outcome with a duration of psychosis \u22642 weeks in half and full remission in two-thirds of patients. In patients with infection, signs of inflammation were reported in 78.3% and increased CRP in 58.6%. While reports on patients with infection are continuously published, no report about patients without infection was found after July 2020.<\/jats:p><\/jats:sec><jats:sec id=\"S0924270822000114_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>Cases without infection were considered reactive and originated all from the first wave of the corona pandemic. In cases with infection, inflammation was considered as the main pathogenetic factor but was not found in all patients. Diagnosis was impeded by the overlap of psychosis with delirium.<\/jats:p><\/jats:sec>","DOI":"10.1017\/neu.2022.11","type":"journal-article","created":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T13:31:34Z","timestamp":1648733494000},"page":"289-310","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":4,"title":["First-episode psychotic disorders in the wake of the COVID-19 pandemic: a descriptive review of 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