{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:53:52Z","timestamp":1785412432954,"version":"3.56.0"},"reference-count":58,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T00:00:00Z","timestamp":1767312000000},"content-version":"unspecified","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Acta Neuropsychiatr."],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0924270825100525_as1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Borderline personality disorder (BPD) is characterised by instability in interpersonal relationships, self-image, and affect. Dysregulated negative emotional processing involving prefrontal and limbic circuits is considered a neural basis of BPD. However, it remains unclear how prefrontal modulation of social decision-making in BPD differs from non-psychiatric controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0924270825100525_as2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      To investigate social decision-making in response to unfairness, we conducted an functional magnetic resonance imaging study involving adults with a diagnosis of BPD (\n                      <jats:italic>n<\/jats:italic>\n                      = 77) and healthy controls (HCs;\n                      <jats:italic>n<\/jats:italic>\n                      = 60). Using an inequality aversion model, we derived parameters of social norm adaptation and inequality sensitivity from behavioural data during a modified ultimatum game designed to measure responses to offer norm shifts. Valence and salience signal-processing models isolated prefrontal activations related specifically to social norm prediction error.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0924270825100525_as3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Cumulative rejection rates indicated that individuals diagnosed with BPD exhibited consistent differences in overall offer rejection rates but similar adaptation to HC when responding to norm shifts. Preservation of normative social decision-making in BPD (no significant difference vs. HC) was evident in regression analyses of rejection rates and in reinforcement learning models, with no group differences observed in Rescorla\u2013Wagner parameters. Furthermore, we detected no significant neural activation differences between groups, although ventral regions of the medial prefrontal cortex were preferentially involved in valence-related rather than salience-related polynomial modulation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0924270825100525_as4\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Contrary to our hypotheses, neither behavioural nor neural responses to economic norm violations differed significantly between BPD and HC groups across one-shot games involving unknown partners. Future research could explore whether more personally relevant or higher-stress social contexts elicit differences not observed here.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/neu.2025.10052","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T06:31:19Z","timestamp":1767335479000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Neuroeconomic adaptation to norm shifts is\u00a0preserved in borderline personality disorder"],"prefix":"10.1017","volume":"38","author":[{"given":"IlHo","family":"Park","sequence":"first","affiliation":[{"name":"Fralin Biomedical Research Institute at VTC, Virginia Tech"},{"name":"Catholic Kwandong University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Campbell","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03v76x132","id-type":"ROR","asserted-by":"publisher"}],"name":"Yale School of Medicine"},{"name":"Yale College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Nolte","sequence":"additional","affiliation":[{"name":"Anna Freud National Centre for Children and Families"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terry","family":"Lohrenz","sequence":"additional","affiliation":[{"name":"Fralin Biomedical Research Institute at VTC, Virginia Tech"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brooks","family":"Casas","sequence":"additional","affiliation":[{"name":"Fralin Biomedical Research Institute at VTC, Virginia Tech"},{"name":"Virginia Tech"},{"name":"Virginia Tech \u2013 Wake Forest School of Biomedical Engineering and Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Fonagy","sequence":"additional","affiliation":[{"name":"Anna Freud National Centre for Children and Families"},{"name":"University College London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet","family":"Feigenbaum","sequence":"additional","affiliation":[{"name":"University College London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. 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Published by Cambridge University Press on behalf of Scandinavian College of Neuropsychopharmacology","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike licence (https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the same Creative Commons licence is used to distribute the re-used or adapted article and the original article is properly cited. The written permission of Cambridge University Press or the rights holder(s) must be obtained prior to any commercial use.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e11"}}