{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T15:32:01Z","timestamp":1778859121991,"version":"3.51.4"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T00:00:00Z","timestamp":1743033600000},"content-version":"unspecified","delay-in-days":85,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Acta Neuropsychiatr."],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>This study focused on the effect of the cognitive behavioural therapy (CBT) combined with aripiprazole on cognitive functions and psychological state of schizophrenia patients. Seventy-eight schizophrenia patients were divided into two groups. One group received aripiprazole with conventional nursing treatment for 3 months (control group, <jats:italic>n<\/jats:italic> = 39), and the other received aripiprazole with CBT for 3 months (observation group, <jats:italic>n<\/jats:italic> = 39) (1 session per week, each session lasting 60 min. In the two groups before and after treatment, the severity of symptoms was evaluated using the Psychiatric Symptom Rating Scale (BPRS). Cognitive function was assessed with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). The Positive and Negative Symptom Scale (PANSS) was utilised to evaluate mental status, while the Generalised Self-Efficacy Scale (GSES) measured psychological state. Additionally, the quality of life was assessed using the General Quality of Life Inventory-74 (GQOLI-74). In the final analysis, post-treatment efficacy and complications for the two groups were counted. Both groups showed significant improvements: BPRS and PANSS scores decreased, while RBANS, GSES, and GQOLI-74 scores increased. The observation group showed greater improvements than the control group. The total improvement rate was 89.74% (35\/39) in the observation group, higher than the 71.79% (28\/39) in the control group. The complication rate was 33.33% (13\/39) in the observation group and 38.46% (15\/39) in the control group. The treatment of CBT combined with aripiprazole for schizophrenia has a significantly positive effect on the cognitive functions and psychological state of patients.<\/jats:p>","DOI":"10.1017\/neu.2025.14","type":"journal-article","created":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T02:40:01Z","timestamp":1743043201000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":3,"title":["Application of cognitive behavioural therapy combined with aripiprazole in the treatment of schizophrenia: a randomised controlled trial"],"prefix":"10.1017","volume":"37","author":[{"given":"Jun","family":"Yan","sequence":"first","affiliation":[{"name":"The Second People\u2019s Hospital of Guizhou Province"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunjie","family":"Li","sequence":"additional","affiliation":[{"name":"The Second People\u2019s Hospital of Guizhou Province"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"He","sequence":"additional","affiliation":[{"name":"The Second People\u2019s Hospital of Guizhou Province"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9724-2207","authenticated-orcid":false,"given":"Jie","family":"Xiong","sequence":"additional","affiliation":[{"name":"The Second People\u2019s Hospital of Guizhou Province"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2025,3,27]]},"reference":[{"key":"S0924270825000146_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e37763"},{"key":"S0924270825000146_ref13","article-title":"The development of paliperidone nanocrystals for the treatment of schizophrenia","volume":"7","author":"Lhaglham","year":"2024","journal-title":"Progress in biomedical engineering (Bristol, England)"},{"key":"S0924270825000146_ref4","first-page":"259","article-title":"Psychiatric diagnosis following the 10th revision of the international classification of diseases (ICD-10)","volume":"61","author":"Dilling","year":"1990","journal-title":"Der Nervenarzt"},{"key":"S0924270825000146_ref25","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2021.717715"},{"key":"S0924270825000146_ref23","doi-asserted-by":"publisher","DOI":"10.1093\/arclin\/acr119"},{"key":"S0924270825000146_ref8","first-page":"326","article-title":"Analysis on application value of Fu\u2019s subcutaneous needling for intercostal pain after surgery of osteoporotic thoracic vertebral compression fracture","volume":"46","author":"Hou","year":"2021","journal-title":"Zhen ci yan jiu = Acupuncture research"},{"key":"S0924270825000146_ref24","doi-asserted-by":"publisher","DOI":"10.1080\/14740338.2020.1832990"},{"key":"S0924270825000146_ref21","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4679(199811)54:7<885::AID-JCLP3>3.0.CO;2-E"},{"key":"S0924270825000146_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2010.09.015"},{"key":"S0924270825000146_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2023.137410"},{"key":"S0924270825000146_ref6","first-page":"CD009608","article-title":"Cognitive behavioural therapy (group) for schizophrenia","volume":"7","author":"Guaiana","year":"2022","journal-title":"The Cochrane database of systematic reviews"},{"key":"S0924270825000146_ref19","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-023-01949-9"},{"key":"S0924270825000146_ref20","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-046603"},{"key":"S0924270825000146_ref28","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-023-02138-4"},{"key":"S0924270825000146_ref1","doi-asserted-by":"publisher","DOI":"10.1177\/070674370104600605"},{"key":"S0924270825000146_ref17","doi-asserted-by":"publisher","DOI":"10.3200\/JRLP.139.5.439-457"},{"key":"S0924270825000146_ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s13679-023-00517-0"},{"key":"S0924270825000146_ref18","doi-asserted-by":"publisher","DOI":"10.1037\/ort0000161"},{"key":"S0924270825000146_ref14","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2024.1383173"},{"key":"S0924270825000146_ref15","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2022.808469"},{"key":"S0924270825000146_ref3","unstructured":"Chand, SP , Kuckel, DP and Huecker, MR (2024) Cognitive Behavior Therapy. 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